Tina Buerki-Thurnherr*a, Lisong Xiaob, Liliane Dienera, Osman Arslanb, Cordula Hirscha, Xenia Maeder-Althausa, Kathrin Griederc, Bruno Wampflerc, Sanjay Mathurb, Peter Wicka & Harald F. Krugaa Empa, Swiss Federal Laboratories for Materials Testing and Technology, Laboratory for Materials-Biology Interactions, Lerchenfeldstrasse, St. Gallen, Switzerlandb Institute of Inorganic Chemistry, University of Cologne, Greinstrasse, Cologne, Germanyc Empa, Swiss Federal Laboratories for Materials Testing and Technology, Laboratory for Biomaterials, Lerchenfeldstrasse, St. Gallen, Switzerland

Tina Buerki-Thurnherr

Lisong Xiao

Liliane Diener

Osman Arslan

Cordula Hirsch

Xenia Maeder-Althaus

Kathrin Grieder

Bruno Wampfler

Sanjay Mathur

Peter Wick

Harald F. Krug

Nanotoxicology

纳米毒理学邀请有关与纳米结构材料的使用和开发相关的人类和环境暴露、危害和风险的研究的贡献。在这种情况下，术语纳米结构材料具有广泛的定义，包括“具有至少一维在纳米尺寸范围内的材料”。这些纳米材料的范围从纳米粒子和纳米药物，到较大材料和复合材料的纳米表面。正在使用和正在开发的纳米材料的范围非常多样化，因此本期刊包括一系列用于有目的地输送到身体（食品、药物、诊断和假肢）和消费品（例如油漆、化妆品、电子产品和服装）的材料)，以及为环境应用（例如修复）设计的颗粒。如果这些材料将它们统一起来并定义了纳米毒理学的范围，那就是纳米尺寸范围。虽然“毒理学”一词表明存在风险，但《纳米毒理学》杂志还旨在涵盖提高纳米材料生产、使用和处置过程中安全性的研究。控制良好的研究表明缺乏与纳米材料相关的暴露、危害或风险，或旨在提高生物相容性的研究受到欢迎和鼓励，因为此类研究将推动纳米技术的进步。此外，许多纳米颗粒的开发旨在改善人类健康（例如抗菌剂），并且再次鼓励此类文章。为了提高质量，纳米毒理学将优先考虑已证明所研究纳米材料特征的出版物。

The journal "Nanotoxicology" invites contributions related to research on human and environmental exposure, hazards, and risks associated with the use and development of nanostructured materials. In this context, the term nanostructured materials is broadly defined to include materials with at least one dimension in the nanoscale range. These nanomaterials range from nanoparticles and nanomedicines to nanocoatings on larger materials and composites. Given the diverse range of nanomaterials currently in use and development, this journal encompasses a variety of materials intended for targeted delivery to the body (such as food, drugs, diagnostics, and prosthetics) and consumer products (like paints, cosmetics, electronics, and clothing), as well as particles designed for environmental applications (e.g., remediation). The unifying aspect of these materials, which defines the scope of nanotoxicology, is their nanoscale dimensions. While the term "toxicology" implies the presence of risks, the journal "Nanotoxicology" also aims to cover research that enhances the safety of nanomaterials during production, use, and disposal. Well-controlled studies demonstrating a lack of exposure, hazards, or risks associated with nanomaterials, or aimed at improving biocompatibility, are welcomed and encouraged, as such research will advance the field of nanotechnology. Additionally, many developments in nanoparticles are aimed at improving human health (e.g., antimicrobial agents), and such articles are likewise encouraged. To enhance quality, the journal "Nanotoxicology" will prioritize publications that have demonstrated the characteristics of the nanomaterials studied.

《Nanotoxicology》期刊邀请有关纳米结构材料使用和开发的研究贡献，特别是人类和环境的暴露、危害和风险。这里的“纳米结构材料”广泛定义为至少有一维在纳米尺寸范围内的材料。这些材料包括纳米粒子、纳米药物，以及更大材料和复合材料的纳米表面。由于正在使用和开发的纳米材料种类繁多，本期刊涵盖了多种用于有目的地输送到人体（如食品、药物、诊断和假肢）和消费品（如油漆、化妆品、电子产品和服装）的材料，以及为环境应用（如修复）设计的颗粒。纳米毒理学的核心在于纳米尺寸范围。尽管“毒理学”一词暗示存在风险，但《Nanotoxicology》期刊同样关注提高纳米材料在生产、使用和处置过程中的安全性。经过良好控制的研究表明与纳米材料相关的暴露、危害或风险缺乏证据，或旨在提高生物相容性的研究，都是受到欢迎和鼓励的，因为这些研究将推动纳米技术的进步。此外，许多纳米颗粒的开发旨在改善人类健康（例如抗菌剂），因此此类文章也受到鼓励。为了提高质量，《Nanotoxicology》期刊将优先考虑已证明所研究纳米材料特征的出版物。

<i>In vitro</i>mechanistic study towards a better understanding of ZnO nanoparticle toxicity

It is demonstrated that ZnO-induced Jurkat cell death is largely an ionic effect involving the extracellular release of high amounts of Zn(II), their rapid uptake by the cells and the induction of a caspase-independent alternative apoptosis pathway that is independent of the formation of ROS.

Category	Quartile
医学	3
医学, 毒理学	2
医学, 纳米科技	3

In vitromechanistic study towards a better understanding of ZnO nanoparticle toxicity

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info