Alcohol abuse is a major health problem worldwide, resulting to extensive admissions in many general hospitals. The overall economic cost of alcohol abuse is enormous worldwide. As a small molecule, alcohol can easily cross membrane barriers and reach different parts of the body very quickly. Attainment of its equilibrium concentration in different cellular compartments depends on the respective water content. Alcohol can affect several parts of the brain, but, in general, contracts brain tissues, destroys brain cells, as well as depresses the central nervous system. Excessive drinking over a prolonged period of time can cause serious problems with cognition and memory. Alcohol interacts with the brain receptors, interfering with the communication between nerve cells, and suppressing excitatory nerve pathway activity. Neuro-cognitive deficits, neuronal injury, and neurodegeneration are well documented in alcoholics, yet the underlying mechanisms remain elusive. The effect can be both direct and/ or indirect. In this review we highlighted the role of alcoholism on the CNS and its impact on human health.

Sukhes Mukherjee

Current Neurovascular Research

当前的神经血管研究为发表科学严谨的研究提供了一个跨平台，这些研究解决了神经科学中神经元和血管起源的疾病机制。该杂志作为一个国际论坛，出版新颖和原创作品以及及时的神经科学研究文章、细胞发育障碍、可塑性和退化学科的全长/迷你评论，弥合了基础科学研究和临床发现之间的差距。当前的神经血管研究强调阐明疾病机制，包括细胞和分子，这可能会影响神经元和血管疾病的独特治疗策略的发展。

Current Neurovascular Research is an interdisciplinary platform dedicated to publishing scientifically rigorous research that explores the mechanisms of neuron and vascular-related diseases in neuroscience. As an international forum, the journal publishes novel and original research findings, as well as timely articles, full-length and mini-reviews in the fields of neuroscience, cellular developmental disorders, plasticity, and degeneration, aiming to bridge the gap between basic scientific research and clinical discoveries. Current Neurovascular Research emphasizes elucidating disease mechanisms, including cellular and molecular studies, which may advance the development of unique therapeutic strategies for neuron and vascular diseases.

《Current Neurovascular Research》是一个跨学科的平台，致力于发表科学严谨的研究，探讨神经科学中神经元和血管相关疾病的机制。作为一个国际论坛，该杂志发布新颖且原创的研究成果，以及及时的神经科学研究文章、细胞发育障碍、可塑性和退化领域的全长和迷你评论，旨在弥合基础科学研究与临床发现之间的差距。《Current Neurovascular Research》强调阐明疾病机制，包括细胞和分子层面的研究，这些研究可能会推动针对神经元和血管疾病的独特治疗策略的发展。

Category	Quartile
医学	4
医学, 临床神经病学	4
医学, 神经科学	4

Alcoholism and its Effects on the Central Nervous System

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