Contents 1. Introduction 2. Morphogenesis in Submerged Cultures 2.1 Hyphal growth 2.2 Submerged sporulation 2.3 A special case: Streptomyces L-forms 3. Molecular Control of Liquid-Culture Morphogenesis 3.1 The tip-organizing center and the cytoskeleton 3.2 Extracellular polymers and pellet morphology 3.3 Proteins that control liquid-culture morphogenesis 3.4 Surface modification of Streptomyces spores 4. The SsgA-Like Proteins 4.1 SsgA-like proteins and morphotaxonomy of actinomycetes 4.2 How does SsgA control hyphal morphogenesis? 4.3 SsgA and SsgB control the localization of FtsZ 5. Environmental and Reactor Conditions 5.1 Culture heterogeneity 5.2 Nutrients and morphology 5.3 Fragmentation 5.4 Relationship between agitation, oxygenation, morphology, and productivity 6. Morphology and Antibiotic Production 6.1 Impact of morphology on antibiotic production 6.2 PCD and antibiotic production 7. Outlook: The Correlation Between Morphology and Production Acknowledgments References

Dino van Dissel

Dennis Claessen

Gilles P. van Wezel

Advances in Applied Microbiology

应用微生物学进展对这个快速发展的领域的最新技术和发现进行了深入的回顾。编辑是公认的专家，格式全面且具有启发性。自 1959 年出版以来，应用微生物学进展一直是微生物学领域阅读最广泛和权威的评论来源之一。最近涵盖的领域包括人类肠道中的细菌多样性、原生动物放牧淡水生物膜、酵母发酵过程中的金属以及通过微阵列对宿主-病原体对话的解释。

The journal "Advances in Applied Microbiology" provides an in-depth review of the latest technologies and discoveries in the rapidly evolving field of applied microbiology. The editorial team consists of recognized experts, and the articles are comprehensive and thought-provoking. Since its inception in 1959, "Advances in Applied Microbiology" has been one of the most widely read and authoritative sources of reviews in the field of microbiology. Recent topics covered include bacterial diversity in the human gut, protozoan grazing on freshwater biofilms, the role of metals in yeast fermentation processes, and the interpretation of host-pathogen interactions through microarray technology.

《Advances in Applied Microbiology》期刊深入回顾了应用微生物学这一快速发展的领域中的最新技术和发现。编辑团队由公认的专家组成，文章格式全面且富有启发性。自1959年创刊以来，《Advances in Applied Microbiology》已成为微生物学领域最受欢迎和权威的评论来源之一。最近的研究领域包括人类肠道中的细菌多样性、原生动物对淡水生物膜的捕食、酵母发酵过程中的金属作用，以及通过微阵列技术对宿主-病原体相互作用的解析。

Category	Quartile
生物学	2
生物学, 生物工程与应用微生物	2
生物学, 微生物学	3

Morphogenesis of Streptomyces in Submerged Cultures

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