Objective: This study aims to examine the incidence of post-chemotherapy perianal infection and its influencing factors in patients with acute leukemia.&lt;br&gt; Methods: A total of 243 patients with acute leukemia who underwent chemotherapy in the Three Gorges Hospital affiliated to Chongqing University, China, between January 2019 and December 2020 were selected as study subjects. In the present retrospective study, patients with post-chemotherapy perianal infection were monitored, and the perianal infection rate and clinical features of perianal infection were determined. Categorical variables were compared using the Chi-square test, and the influencing factors of post-chemotherapy perianal infection in patients with acute leukemia were evaluated using logistic analysis.&lt;br&gt; Results: A total of 24 patients (9.88%) with acute leukemia suffered post-chemotherapy perianal infection. Age, basic perianal disease (hemorrhoids) history, constipation, diarrhea, duration of agranulocytosis, and length of hospital stay were compared among the patients. Perianal disease classification, perianal ultrasound, colonoscopy, postoperative pathology, and other clinical data were compared and discussed in relation to the occurrence and development of the disease. The results showed that there were no significant differences in perianal infection degrees between genders and among different types of leukemia (p &gt; 0.05). There were no statistically significant differences in age, pain score, minimum white blood cell count, deficiency duration, and length of hospital stay among patients with different degrees of infection. The Spearman rank correlation test showed that the perianal infection degree was positively correlated with the highest hypersensitive C-reactive protein (hs-CRP) level (p &lt; 0.05). The difference was statistically significant; the higher the maximum hs-CRP/procalcitonin levels, the more serious the perianal infection.&lt;br&gt; Conclusions: Perianal infections are common in the procession of chemotherapy or myelosuppression. This is worthy of clinical recognition. Early recognition of perianal infection and the strengthening of infection risk factor control may be beneficial to improving the subjective feelings of patients with acute leukemia undergoing chemotherapy.

Shasha Wang

Ying Li

Daoyong Jia

Yi Yang

Sisi Wu

Sheng Wang

Bangshuo Zhang

Jianbin Chen

Acupuncture & Electro-Therapeutics Research

该杂志的宗旨是为针灸、电疗及相关领域的基础和临床研究的交流和促进提供一个国际论坛。该杂志的成立是为了通过基于科学学科的多学科研究，使针灸和电疗成为普遍接受的医学分支。最终目标是更好地了解这些治疗的利弊，以补充或改进西方和东方医学中现有的诊断、预后、治疗和预防方法。

The journal "Acupuncture and Electro-Therapeutics Research" aims to provide an international forum for the exchange and promotion of fundamental and clinical research in the fields of acupuncture, electrotherapy, and related areas. The establishment of this journal is intended to make acupuncture and electrotherapy widely accepted branches of medicine through multidisciplinary research based on scientific disciplines. The ultimate goal is to better understand the advantages and disadvantages of these treatments to complement or improve existing diagnostic, prognostic, therapeutic, and preventive methods in both Western and Eastern medicine.

《Acupuncture and Electro-Therapeutics Research》旨在为针灸、电疗及相关领域的基础和临床研究提供一个国际交流与促进的平台。该杂志的成立旨在通过多学科的科学研究，使针灸和电疗成为广泛认可的医学分支。最终目标是更好地理解这些治疗方法的优缺点，以补充或改进西方和东方医学中现有的诊断、预后、治疗和预防策略。

Category	Quartile
医学	4
医学, 全科医学与补充医学	4
医学, 神经科学	4

Post-Chemotherapy Clinical Perianal Infection Features in Patients with Acute Leukemia

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