Dyslipidemia is the leading cause of cardiovascular mortality and morbidity.Reduction of lipids, particularly low-density lipoprotein cholesterol (LDL-C), with statins, significantly decreases the risk of cardiovascular events.Among different statins, pitavastatin, exhibits a peculiar pharmacokinetic and pharmacological profile.Indeed, differently from other statins, pitavastatin: a) is not metabolized by hepatic cytochrome CYP3A4 isoenzyme, therefore has a very low drug-drug interaction; b) has a similar or greater effect on LDL-C, c) is not associated with glucose metabolism impairment, and the risk of new onset diabetes is very low, d) increases high density lipoproteins (HDL) levels and, particularly, improves cholesterol efflux capacity of HDL, d) decreases cardiovascular outcome in primary and secondary prevention.

Francesco Fici

Bahar Arican Tarim

Gökhan Faikoğlu

Elif İlkay Yüce

Baris Güngör

Nicolas Roberto Robles

ACTA Pharmaceutica Sciencia

Acta Pharmaceutica Sciencia (Acta Pharm. Sci.), formerly known as Bulletin of Pharmacy and Acta Pharmaceutica Turcica is a peer-reviewed scientific journal publishing current research and reviews covering all fields of pharmaceutical sciences since 1953.    The original studies accepted for publication must be unpublished work and should contain data that have not been published elsewhere as a whole or a part. The reviews must provide critical evaluation of the state of knowledge related with the subject.    All manuscripts has to be written in clear and concise English.       Starting from 2016, the journal will be issued quarterly both in paper and on-line formates also publish special issues for national or international scientific meetings and activities in the coverage field.

Acta Pharmaceutica Sciencia (Acta Pharm. Sci.) is a peer-reviewed scientific journal that has been publishing current research and reviews covering all fields of pharmaceutical sciences since 1953. Formerly known as Bulletin of Pharmacy and Acta Pharmaceutica Turcica, the journal accepts original studies that must be unpublished work and contain data that have not been published elsewhere in whole or in part. Reviews must provide a critical evaluation of the state of knowledge related to the subject. All manuscripts must be written in clear and concise English. Starting from 2016, the journal is issued quarterly in both paper and online formats and also publishes special issues for national or international scientific meetings and activities in the coverage field.

《Acta Pharmaceutica Sciencia》（《药学学报》）是一本经过同行评审的科学期刊，自1953年起出版，涵盖药学科学的各个领域，前身为《药学公报》和《土耳其药学学报》。该期刊接受的原创研究必须是未发表的工作，且所含数据不得在其他地方以整体或部分形式发表。综述文章需对相关主题的知识现状进行批判性评估。所有稿件必须用清晰简练的英语撰写。自2016年起，该期刊将以纸质和在线形式每季度出版，并为国家或国际科学会议及活动出版特刊。

Pitavastatin: Similarities and Differences Compared With Other Statins

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