The authors studied the effects of environmental cadmium exposure on blood pressure (BP). Subjects 1140 men and 1713 women, aged > or =50 yr lived in three areas of Japan considered "unpolluted" by cadmium. Multiple logistic regression analysis was used to evaluate relationships between hypertension/nonhypertension and cadmium concentrations in blood (B-Cd) or urine (U-Cd). Age, body mass index, drinking and smoking habits, and blood and urine chemistry data were incorporated into the model. Odds ratios for hypertension were significantly less than 1 in either gender when U-Cd was the indicator of cadmium exposure and hypertension was defined as systolic BP > or =140 mmHg and/or diastolic BP > or =90 mmHg. The results suggest a significant negative association between cadmium exposure and BP in inhabitants in Japan.

Isao Kurihara

Etsuko Kobayashi

Yasushi Suwazono

Mirei Uetani

Takeya Inaba

Mitsuhiro Oishiz

Teruhiko Kido

Hideaki Nakagawa

Koji Nogawa

Archives of Environmental Health An International Journal

Archives of Environmental Health

Association Between Exposure to Cadmium and Blood Pressure in Japanese Peoples

日本人群中镉暴露与血压的关联

Association Between Exposure to Cadmium and Blood Pressure in Japanese Peoples

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