Ru-Catalyzed Redox-Neutral Coupling of N-Chlorobenzamides with Unsymmetrical Alkynes in Water
水相中Ru催化N-氯苯甲酰胺与不对称炔烃的氧化还原中性偶联
Sharajit Saha, Hemanga Bhattacharyya, Subhankar Dolai, Swati Samantaray, Kshitiz Verma, Tharmalingam Punniyamurthy
期刊: The Journal of Organic Chemistry
摘要
In water, Ru-catalyzed annulation of N-chlorobenzamides with unsymmetrical internal alkynes bearing aryl, hydroxy, ester, and sulfonyl functionalities has been accomplished to afford isoquinolone scaffolds under external oxidant-free conditions at room temperature. Use of water as reaction medium, redox-neutral conditions, regioselectivity, and substrate scope are important practical features.
文章解读
研飞AI智能解析 PDF,回答研究者问题,助你秒懂论文
免费下载期刊信息
期刊:
ISSN: 0022-3263
国际分区
类目 | 分区 |
CHEMISTRY, ORGANIC | 1 |
国内分区
类目 | 分区 |
化学 | 2 |
化学, 有机化学 | 2 |