Indole alkaloids are heterocyclic natural products with extensive pharmacological activities. As an important source of lead compounds, many clinical drugs have been derived from natural indole compounds. Marine indole alkaloids, from unique marine environments with high pressure, high salt and low temperature, exhibit structural diversity with various bioactivities, which attracts the attention of drug researchers. This article is a continuation of the previous two comprehensive reviews and covers the literature on marine indole alkaloids published from 2015 to 2021, with 472 new or structure-revised compounds categorized by sources into marine microorganisms, invertebrates, and plant-derived. The structures and bioactivities demonstrated in this article will benefit the synthesis and pharmacological activity study for marine indole alkaloids on their way to clinical drugs.

Yong Hu

Siling Chen

Fang Yang

Shuai Dong

Marine Drugs

MARINE DRUGS (ISSN 1660-3397) 发表关于海洋药物研究、开发和生产的评论、定期研究论文和简短说明。我们的目标是鼓励科学家尽可能详细地发表他们的实验和理论研究，特别是生物活性化合物的合成程序和表征信息。实验部分的长度没有限制。

Marine Drugs (ISSN 1660-3397) publishes reviews, regular research articles, and short communications on the research, development, and production of marine drugs. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible, particularly regarding the synthesis procedures and characterization information of bioactive compounds. There is no limit on the length of the experimental section.

《Marine Drugs》 (ISSN 1660-3397) 发表关于海洋药物的研究、开发和生产的评论、定期研究论文和简短说明。我们的目标是鼓励科学家尽可能详细地发表他们的实验和理论研究，特别是生物活性化合物的合成程序和表征信息。实验部分的长度没有限制。

Marine Indole Alkaloids—Isolation, Structure and Bioactivities

The structures and bioactivities demonstrated in this article will benefit the synthesis and pharmacological activity study for marine indole alkaloids on their way to clinical drugs.

Category	Quartile
医学	2
医学, 药物化学	2
医学, 药学	2

Marine Indole Alkaloids—Isolation, Structure and Bioactivities

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info

Category	Quartile
PHARMACOLOGY & PHARMACY	1