Abstract Lung cancer is the second leading cause of the mortality related to the cancer. So, it is very necessary to explore the novel strategies to eradicate it. Currently, gold based medicinal compounds have emerged as remarkable anticancer agents and expressed strong potential against the lung cancer cell lines. This review provides a comprehensive overview of the history, advancements, and recent state of gold complexes in the treatment of the lung cancer. We discuss the biological evaluation in relation with the chemical structures of numerous gold complexes, including those featuring thiosemicarbazone, N -heterocyclic imine, N -heterocyclic carbenes, steroidyl NHC, CAACs, carbamates, and diphosphanes as ligands. Gold complexes’ cytotoxicity has been assessed and contrasted with that of standard drugs such as auranofin and cisplatin, with a special focus on IC 50 values for evaluating potency. This review targets to deliver a detailed understanding of the potential of the gold complexes in lung cancer therapies, paving way for the future research and clinical applications.

Aqsa Hanif

Sawsan S. Al-Rawi

Ahmad H. Ibrahim

Abbas Washeel Salman

Ayesha Zafar

Muhammad Adnan Iqbal

Sana Batool

Ghazanfar Abbas

Reviews in Inorganic Chemistry

无机化学评论 (REVIC) 是一本同行评议的季刊，重点关注无机化学的发展。技术评论提供详细的合成方案、方法评论和设备描述。从综合、理论或分析的角度处理主题。编辑和出版商致力于高质量标准和快速处理审查和出版过程。该杂志出版固态、分子和表面化学的各个方面。可以从综合的、理论的或分析的角度来处理主题。编辑和出版商致力于高质量标准和快速处理审稿和出版过程。主题：-主族化学-过渡金属化学-配位化学-有机金属化学-催化-生物无机化学-超分子化学-离子液体

Reviews in Inorganic Chemistry is a peer-reviewed quarterly journal that focuses on the latest developments in the field of inorganic chemistry. The journal provides detailed synthesis protocols, method reviews, and equipment descriptions, covering various aspects of solid-state, molecular, and surface chemistry. Articles can be approached from comprehensive, theoretical, or analytical perspectives. The editors and publishers are committed to maintaining high-quality standards and ensuring a swift review and publication process. Key topics include main group chemistry, transition metal chemistry, coordination chemistry, organometallic chemistry, catalysis, bioinorganic chemistry, supramolecular chemistry, and ionic liquids.

《Reviews in Inorganic Chemistry》是一本同行评审的季刊，专注于无机化学领域的最新进展。该期刊提供详细的合成方案、方法评论和设备描述，涵盖固态、分子和表面化学的各个方面。文章可以从综合、理论或分析的角度进行探讨。编辑和出版商致力于维持高质量的标准，并快速处理审稿和出版流程。主要主题包括：主族化学、过渡金属化学、配位化学、有机金属化学、催化、生物无机化学、超分子化学和离子液体。

Category	Quartile
化学	3
化学, 无机化学与核化学	2

Gold complexes: a new frontier in the battle against lung cancer

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Journal Info

Category	Quartile
CHEMISTRY, INORGANIC & NUCLEAR	1