Abstract The numerous attempts to prove a therapeutic effect of low-dose colchicine for the treatment of Coronavirus disease-2019 (COVID-19) have been discouraging. Increase of doses, however, leads to accumulation in leukocytes and inhibition of the cytokine storm thus preventing COVID-19 complications and hospitalizations. Hospital mortality drops up to 7-fold, while outpatients practically do not reach hospitalization.

V. Mitev

Acta Medica Bulgarica

About 30 years ago - in 1973, on the initiative of the Publishing House „Medicine and Physical Culture", namely its former director Mr. Traian Ivanov, the Ministry of Health set up and accepted to subsidize a new medical magazine that was to be published only in the English language and had to reflect the status and the achievements of the Bulgarian medical science.   Thus the language barrier was overcome and stable relations were established with the international medical society, large libraries, and university centers.   The famous internationally known scientist professor Assen A. Hadjiolov was elected edition-in-chief by the first editorial staff and the magazine was named Acta Medica Bulgarica.

Acta Medica Bulgarica was established in 1973, initiated by the Publishing House of Medicine and Physical Culture, under the leadership of its former director, Mr. Traian Ivanov. The Ministry of Health set up and subsidized a new medical journal that was to be published exclusively in English, aiming to reflect the status and achievements of Bulgarian medical science. This initiative overcame the language barrier and established stable relations with the international medical community, large libraries, and university centers. The renowned international scientist, Professor Assen A. Hadjiolov, was elected as the editor-in-chief by the first editorial board, and the journal was named Acta Medica Bulgarica.

《Acta Medica Bulgarica》创办于1973年，源于医学与体育文化出版社的倡议，时任社长Traian Ivanov先生的推动下，保健部设立并资助了一本新的医学杂志，该杂志仅用英语出版，旨在反映保加利亚医学科学的现状和成就。通过这一举措，克服了语言障碍，建立了与国际医学界、大型图书馆和大学中心的稳定关系。著名国际科学家Assen A. Hadjiolov教授被第一届编辑部选为主编，杂志因此命名为《Acta Medica Bulgarica》。

High Colchicine Doses Are Really Silver Bullets Against COVID-19

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