Among the most prominent realizations of Morris J. Robins in the antiviral nucleoside chemistry are (i) the synthesis of 8-substituted (methyl-, amino-, bromo-, iodo) derivatives of acyclovir, (ii) xylotubercidin as an inhibitor of herpes simplex virus (HSV) infections, (iii) the anti-HIV activity of the 2',3'-dideoxyriboside of 2,6-diaminopurine (ddDAPR) and the 3'-azido- and 3'-fluoro derivatives thereof (AzddDAPR and FddDAPR, respectively), (iv) the potentiating effect of ribavirin on the anti-HIV activity of 2',3'-dideoxyinosine (ddI) and ddDAPR, (v) S-adenosylhomocysteine hydrolase (SAH) inhibitors principally active against vaccinia virus (VV) and vesicular stomatitis virus (VSV), and (vi) furo[2,3-d]pyrimidinone derivatives active against varicella-zoster virus (VZV).

Erik De Clercq

Nucleosides Nucleotides & Nucleic Acids

NUCLEOSIDES、NUCLEOTIDES & NUCLEIC ACIDS 发表研究文章、简短通知以及对相关主题的简明、批判性评论，重点关注核苷、核苷酸和核酸的化学和生物学。这本全包期刊包含实验细节，强调合成、生物活性、新的和改进的合成方法，以及与新化合物相关的重要观察。

The journal "Nucleosides, Nucleotides and Nucleic Acids" publishes research articles, brief communications, and concise critical reviews on related topics, focusing on the chemistry and biology of nucleosides, nucleotides, and nucleic acids. This comprehensive journal includes experimental details, emphasizing synthesis, bioactivity, new and improved synthetic methods, and significant observations related to new compounds.

《Nucleosides, Nucleotides and Nucleic Acids》期刊发表研究文章、简短通知以及对相关主题的简明、批判性评论，重点关注核苷、核苷酸和核酸的化学与生物学。这本综合性期刊包含实验细节，强调合成、生物活性、新的和改进的合成方法，以及与新化合物相关的重要观察。

Category	Quartile
生物学	4
生物学, 生化与分子生物学	4

In memory of an exquisite medicinal chemist, Prof. Morris Robins

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Journal Info

Category	Quartile
BIOCHEMISTRY & MOLECULAR BIOLOGY	4