Transition metal complexes have a great potential as therapeutic agents in the field of oncology. Metals are necessary cellular components that are required for various vital cellular and biochemical functions for living beings. Metallodrugs have a unique mode of action against cancer cells depending on the metal used, oxidation state, types and numbers of corresponding ligands as well as the coordination geometry. Coordination complexes become highly desirable probes as potential anticancer agents and can be used as drugs or prodrugs. The discovery of cisplatin was a turning point that sparked interest in metal coordination complexes as potential anticancer medications. As a result, scientists are focusing on alternative possible metals for anticancer activities including titanium, rhodium, gallium, germanium, iridium, ruthenium, copper, gold, and molybdenum. This review explores the promising ruthenium and iron complexes that are attracting attention in cancer research, with a focus on their potential therapeutic use. Also highlights promising ruthenium and iron complexes with their unique uptake mechanisms and their potential to target specific organelles.

Neppoliyan Kannan

Vidya Radhakrishnan

Arup Sinha

Inorganic Chemistry Communications

《无机化学通讯》创刊于 1998 年 1 月，是一本国际期刊，致力于快速发表无机、有机金属和超分子化学主要领域的短篇通讯。主题包括合成和反应化学、反应动力学和机制、生物无机化学、光化学以及金属和有机金属化合物在化学计量和催化合成或有机化合物中的应用。

Inorganic Chemistry Communications, established in January 1998, is an international journal dedicated to the rapid publication of short communications in the fields of inorganic chemistry, organometallic chemistry, and supramolecular chemistry. The topics covered include synthesis and reaction chemistry, reaction kinetics and mechanisms, bioinorganic chemistry, photochemistry, and the applications of metal and organometallic compounds in stoichiometry, catalytic synthesis, or organic compounds.

《无机化学通讯》创刊于1998年1月，是一本国际期刊，专注于快速发表无机化学、有机金属化学和超分子化学领域的短篇通讯。期刊涵盖的主题包括合成与反应化学、反应动力学与机制、生物无机化学、光化学，以及金属和有机金属化合物在化学计量、催化合成或有机化合物中的应用。

Category	Quartile
化学	3
化学, 无机化学与核化学	3

Unveiling the anticancer activity of ruthenium and iron complexes

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Journal Info

Category	Quartile
CHEMISTRY, INORGANIC & NUCLEAR	1