Sports nutrition supplements have previously been reported to contain undeclared doping substances. The use of such supplements can lead to general health risks and may give rise to unintentional doping violations in elite sports. To assess the prevalence of doping substances in a range of high-risk sports nutrition supplements available from Dutch web shops. A total of 66 sports nutrition supplements - identified as potentially high-risk products claiming to modulate hormone regulation, stimulate muscle mass gain, increase fat loss, and/or boost energy - were selected from 21 different brands and purchased from 17 web shops. All products were analyzed for doping substances by the UK life sciences testing company LGC, formerly known as the Laboratory of the Government Chemist, using an extended version of their ISO17025 accredited nutritional supplement screen. A total of 25 out of the 66 products (38%) contained undeclared doping substances, which included high levels of the stimulants oxilofrine, β-methylphenethylamine (BMPEA) and N,β-dimethylphenethylamine (NBDMPEA), the stimulant 4-methylhexan-2-amine (methylhexaneamine, 1,3-dimethylamylamine, DMAA), the anabolic steroids boldione (1,4-androstadiene-3,17-dione) and 5-androstene-3β,17α-diol (17α-AED), the beta-2 agonist higenamine and the beta-blocker bisoprolol. Based upon the recommended dose and the potential variability of analyte concentration, the ingestion of some products identified within this study could pose a significant risk of unintentional doping violations. In addition to inadvertent doping risks, the prescribed use of 3 products (4.5%) could likely impose general health risks.

Erik Duiven

Luc J.C. van Loon

Laila Spruijt

Willem Koert

Olivier M. de Hon

Journal of Sports Science and Medicine

JOURNAL OF SPORTS SCIENCE AND MEDICINE (JSSM) 是一本非盈利性科学电子期刊，发表运动医学和运动科学领域的研究和评论文章以及案例研究。 JSSM 每季在 3 月、6 月、9 月和 12 月发布。 JSSM 还出版社论、“致编辑的信”部分、国际和国家代表大会、小组会议、会议和专题讨论会的摘要，并可作为当前关注的重大问题的公开讨论论坛。

The Journal of Sports Science and Medicine (JSSM) is a non-profit scientific electronic journal that publishes research articles, review articles, and case studies in the fields of sports medicine and sports science. JSSM is published quarterly in March, June, September, and December. The journal also includes editorials, letters to the editor, abstracts from international and national conferences, panel meetings, and symposiums, serving as a public forum for discussing significant current issues.

《Journal of Sports Science and Medicine》（JSSM）是一份非盈利性的科学电子期刊，专注于运动医学和运动科学领域的研究、评论文章以及案例研究。JSSM 每年发布四期，分别在 3 月、6 月、9 月和 12 月。期刊还包括论文、致编辑的信件、国际和国家代表大会、小组会议、会议和专题讨论会的摘要，并为当前重大问题提供公开讨论的论坛。

Undeclared Doping Substances are Highly Prevalent in Commercial Sports Nutrition Supplements

Based upon the recommended dose and the potential variability of analyte concentration, the ingestion of some products identified within this study could pose a significant risk of unintentional doping violations.

Category	Quartile
医学	2
医学, 运动科学	2

Undeclared Doping Substances are Highly Prevalent in Commercial Sports Nutrition Supplements

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Journal Info

Category	Quartile
SPORT SCIENCES	2