Abstract The sympathetic nervous system inhibits gut motility, secretion, and blood flow in the gut microvasculature and can modulate gastrointestinal inflammation. Sympathetic neurons signal via catecholamines, neuropeptides, and gas mediators. In the current review, we summarize the current understanding of the mature sympathetic innervation of the gastrointestinal tract with a focus mainly on the prevertebral sympathetic ganglia as the main output to the gut. We also highlight recent work regarding the developmental processes of sympathetic innervation. The anatomy, neurochemistry, and connections of the sympathetic prevertebral ganglia with different parts of the gut are considered in adult organisms during prenatal and postnatal development and aging. The processes and mechanisms that control the development of sympathetic neurons, including their migratory pathways, neuronal differentiation, and aging, are reviewed.

Petr M. Masliukov

Andrey I. Emanuilov

Antonina F. Budnik

The Anatomical Record

The Anatomical Record is a journal dedicated to anatomical research, covering various fields related to anatomy. It aims to provide researchers with a platform to communicate and share the latest research findings.

《Anatomical Record》是一本专注于解剖学研究的期刊，涵盖了与解剖学相关的各个领域，旨在为研究者提供一个交流和分享最新研究成果的平台。

Anatomical Record

Sympathetic innervation of the development, maturity, and aging of the gastrointestinal tract

The current understanding of the mature sympathetic innervation of the gastrointestinal tract is summarized with a focus mainly on the prevertebral sympathetic ganglia as the main output to the gut.

Category	Quartile
医学	4
医学, 解剖学与形态学	4

Sympathetic innervation of the development, maturity, and aging of the gastrointestinal tract

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Journal Info

Category	Quartile
ANATOMY & MORPHOLOGY	2