Spinal cord injury (SCI) is catastrophic and can culminate in disability and death. The routine therapy employed in early stages of SCI currently entails surgical procedures combined with high doses of methylprednisolone (MP). MP is highly controversial for the lack of consensus on its true therapeutic effects. Resveratrol (RES) has recently been recognized as a potential and novel therapeutic drug in SCI. Herein, we investigated the effect of RES in a SCI rat-model and found significant improvement in Basso-Beattie-Bresnahan scores. Results obtained from histological, immunohistochemistry, and ultra-structural examinations evidenced the tremendous treatment effect of RES. On the basis of our experimental results, we hypothesize that RES could serve as an effective SCI therapeutic with prolong treatment time following injury.

Xuehong Liu

Benson O.A. Botchway

Xiaoning Tan

Yong Zhang

Marong Fang

Microscopy Research and Technique

显微镜研究与技术 (MRT) 发表关于先进显微镜原始架构和方法的各个方面的文章，并在生物、临床、化学和材料科学中得到应用。鼓励原始的基础和应用研究以及处理各种显微镜子集的技术论文。 MRT 是开发新显微镜方法或使用显微镜回答基础和应用研究中关键问题的正确形式。

The journal "Microscopy Research and Technique" publishes research articles on various aspects of advanced microscopy principles and methods, applied across biological, clinical, chemical, and materials science fields. The journal encourages original fundamental and applied research, as well as technical papers addressing various microscopy techniques. MRT serves as an ideal platform for developing new microscopy methods or using microscopy to address critical questions in fundamental and applied research.

《Microscopy Research and Technique》期刊发表关于先进显微镜原理和方法的研究文章，涵盖生物、临床、化学和材料科学等多个领域。期刊鼓励原创的基础和应用研究，以及针对各种显微镜技术的论文。MRT 是开发新显微镜方法或利用显微镜解决基础和应用研究中关键问题的理想平台。

Resveratrol treatment of spinal cord injury in rat model

Investigation of the effect of RES in a SCI rat‐model found significant improvement in Basso–Beattie–Bresnahan scores and hypothesize that RES could serve as an effective SCI therapeutic with prolong treatment time following injury.

Category	Quartile
工程技术	3
工程技术, 显微镜技术	1
工程技术, 解剖学与形态学	2
工程技术, 生物学	3

Resveratrol treatment of spinal cord injury in rat model

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