Primary hypokalemic periodic paralysis (HypoPP) is a muscle channelopathy that can cause periodic paralysis and permanent weakness. Currently, little is known about how progressive this myopathy is. Natural history data for HypoPP can potentially answer the question of progressiveness and form the basis for outcome measures to be used in follow-up and emerging treatment trials. We aimed to describe the natural history of HypoPP and assess whether quantitative fat imaging is a valuable biomarker to monitor disease progression.

Sonja Holm-Yildiz

Thomas Krag

Tina Dysgaard

Britt Stævnsbo Pedersen

Nanna Witting

Louise Sloth Kodal

Linda Kannuberg

Jonas Jalili Pedersen

Zhe Lyu

Morten Müller Aagaard

John Vissing

Neurology Genetics

NEUROLOGY: GENETICS 是一本在线开放获取期刊，发表神经遗传学领域的同行评议报告。神经遗传学所有领域的原创文章都将发表，包括罕见和常见的遗传变异、基因型-表型相关性、已知疾病基因突变导致的异常表型以及与疾病有推定联系的遗传变异。这将包括报告遗传疾病风险和药物基因组学的研究。此外，NEUROLOGY: GENETICS 将发布基于基因的临床试验（病毒、ASO 等）的结果。基因工程模型系统不是神经病学的主要关注点：遗传学，但欢迎使用模型系统进行治疗试验的研究，包括报告阴性结果的有力研究。

Neurology: Genetics is an online open-access journal dedicated to peer-reviewed research in the field of neurogenetics. The journal welcomes original articles covering all aspects of neurogenetics, including rare and common genetic variants, genotype-phenotype correlations, abnormal phenotypes resulting from known disease gene mutations, and genetic variants with presumed links to diseases. Additionally, Neurology: Genetics will publish research related to genetic disease risk and pharmacogenomics. While gene-engineered model systems are not the primary focus of neurology, studies utilizing model systems for therapeutic trials, including robust studies reporting negative results, are also welcomed.

《Neurology: Genetics》是一本在线开放获取期刊，专注于神经遗传学领域的同行评审研究。该期刊欢迎发表所有与神经遗传学相关的原创文章，包括罕见和常见的遗传变异、基因型与表型的相关性、已知疾病基因突变导致的异常表型，以及与疾病相关的潜在遗传变异。此外，《Neurology: Genetics》还将发布与遗传疾病风险和药物基因组学相关的研究成果。期刊也欢迎基于基因的临床试验（如病毒、ASO等）的结果，但基因工程模型系统并不是神经病学的主要关注点，然而，使用模型系统进行治疗试验的研究，包括报告阴性结果的研究，仍然受到欢迎。

Category	Quartile
医学	3
医学, 临床神经病学	3
医学, 遗传学	3

Quantitative Muscle MRI to Monitor Disease Progression in Hypokalemic Period Paralysis

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info