BioEssaysVolume 41, Issue 1 1800215 Thoughts & Opinion A Perspective on the Potential Utility of a Viscosupplement Multifunctional Biotherapeutic Proteoglycan-4: From mere lubricant to regulator of tissue homeostasis and inflammation James Melrose, James Melrose Raymond Purves Bone and Joint Research Laboratory, Kolling Institute, Northern Sydney Local Health District, St. Leonards, NSW 2065, Australia Sydney Medical School, Northern, The University of Sydney, Sydney, NSW 2052, Australia Faculty of Medicine and Health, The University of Sydney, Royal North Shore Hospital, St. Leonards, NSW 2065, Australia Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, AustraliaSearch for more papers by this author James Melrose, James Melrose Raymond Purves Bone and Joint Research Laboratory, Kolling Institute, Northern Sydney Local Health District, St. Leonards, NSW 2065, Australia Sydney Medical School, Northern, The University of Sydney, Sydney, NSW 2052, Australia Faculty of Medicine and Health, The University of Sydney, Royal North Shore Hospital, St. Leonards, NSW 2065, Australia Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, AustraliaSearch for more papers by this author First published: 30 November 2018 https://doi.org/10.1002/bies.201800215Citations: 2 This article comments on the Hypothesis paper by Nabangshu Das et al., https://doi.org/10.1002/bies.201800166 Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume41, Issue1January 20191800215 RelatedInformation

James Melrose

BioEssays

分子 - 细胞 - 生物医学 - 生理学 - 转化研究 - 系统 - 鼓励假设 BIOESSAYS 是一份经过同行评审、审查和讨论的期刊。我们的目标是在分子、遗传、细胞或生理维度上发表当代生物学的新颖见解、前瞻性评论和评论，并作为这些领域新思想的讨论论坛。另一个目标是鼓励在有机体研究、系统方法和生态系统方面的跨学科和综合生物学，在适当的情况下。

BioEssays is a peer-reviewed journal that focuses on molecular, cellular, biomedical, physiological, translational research, and systems biology. Our aim is to publish novel insights, forward-looking reviews, and comprehensive commentaries in contemporary biology, serving as a forum for discussion of new ideas in these fields. Additionally, we encourage interdisciplinary and integrative biology research in organism studies, systems approaches, and ecosystems where appropriate.

BioEssays 是一本经过同行评审的期刊，专注于分子、细胞、生物医学、生理学、转化研究和系统生物学等领域。我们的目标是发表当代生物学的新颖见解、前瞻性评论和综合评述，并为这些领域的新思想提供讨论平台。此外，我们还鼓励在有机体研究、系统方法和生态系统方面的跨学科和综合生物学研究。

A Perspective on the Potential Utility of a Viscosupplement Multifunctional Biotherapeutic

The development of multifunctional biotherapeutics which combine attributes of a polymers material properties with beneficial biological or cell directive properties is an attractive innovative approach of great potential benefit in the protection and function of diarthrodial joint tissues.

Category	Quartile
生物学	3
生物学, 生物学	3
生物学, 生化与分子生物学	4

A Perspective on the Potential Utility of a Viscosupplement Multifunctional Biotherapeutic

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