Understanding the rapidly evolving landscape of single-cell and spatial omic technologies is crucial for advancing biomedical research and drug development. We provide a living review of both mature and emerging commercial platforms, highlighting key methodologies and trends shaping the field. This review spans from foundational single-cell technologies such as microfluidics and plate-based methods to newer approaches like combinatorial indexing; on the spatial side, we consider next-generation sequencing and imaging-based spatial transcriptomics. Finally, we highlight emerging methodologies that may fundamentally expand the scope for data generation within pharmaceutical research, creating opportunities to discover and validate novel drug mechanisms. Overall, this review serves as a critical resource for navigating the commercialization and application of single-cell and spatial omic technologies in pharmaceutical and academic research.

Joachim De Jonghe

James W Opzoomer

Amaia Vilas-Zornoza

Benedikt S Nilges

Peter Crane

Marco Vicari

Hower Lee

David Lara-Astiaso

Torsten Gross

Jörg Morf

Kim Schneider

Juliana Cudini

Lorenzo Ramos-Mucci

Dylan Mooijman

Katarína Tiklová

Sergio Marco Salas

Christoffer Mattsson Langseth

Nachiket D Kashikar

Denis Schapiro

Joakim Lundeberg

Mats Nilsson

Alex K Shalek

Adam P Cribbs

Jake P Taylor-King

Cell Genomics

scTrends: A living review of commercial single-cell and spatial 'omic technologies

scTrends：商业单细胞和空间组学技术的动态综述

scTrends: A living review of commercial single-cell and spatial 'omic technologies

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Journal Info

Category	Quartile
GENETICS & HEREDITY	1