Although lab-coat genomics scientists are highly skilled and involved in pioneering work, few studies have examined their perceptions on what they do, and how they relate with others in interdisciplinary work. Recognizing that gap, we were curious to talk with scientists about their current work and positionalities related to the use of genomics for bioremediation. Using unstructured open-ended interviews and thematic analysis, we interviewed researchers with diverse genomics-related expertise. Emerging topics were grouped into two broad categories akin to Bronfenbrenner’s nested developmental model: microsystem matters, comprising technical advances, barriers, and localized concerns; and macrosystem matters, exploring wider reflections and the philosophies of genomics and society. At the microsystem level, findings revealed differences of opinion about methodological steps, but there was agreement about the incompleteness of databases and the absence of established reference values. These two problems may not only impact a project’s progress but also the ability to gauge success, affecting budgeting, human resource needs, and overall stress. At the macrosystem level, scientists voiced concerns about how different social groups perceive and accept genomics applications, as those tend to be viewed by lay persons as genetic interventions. Another focus was on how academic publication slows progress because it is orientated toward positive results while gaps in knowledge could be filled by publishing negative results or methodological barriers. This study underscores scientists’ self-awareness within the genomics discipline, acknowledging how their beliefs and biases shape research outcomes. It illuminates critical reflections essential for navigating societal and scientific landscapes in genomics research.

Renata Mont’Alverne Bretz Giovanini

Lori Bradford

Cheryl Buckmaster

Graham Strickert

Jason MacLean

Diane Dupont

Frontiers in Genetics

FRONTIERS IN GENETICS 发表了经过严格同行评审的关于与生命的所有领域相关的基因和基因组的研究，从人类到植物，再到牲畜和其他模式生物。这本多学科、开放获取的期刊由世界领先专家组成的杰出编辑委员会领导，处于向研究人员、学者、临床医生、政策制定者和公众传播前沿研究的前沿。遗传研究及其影响各种生物过程的基因组有据可查。然而，大多数发现仍有待发现。一个新时代正在见证基因组功能和变异性、遗传和基因组工具的使用以及各种生物现象的遗传基础分析方面的重大发展。

Frontiers in Genetics publishes rigorously peer-reviewed research on genes and genomes related to all fields of life, from humans to plants, livestock, and other model organisms. This multidisciplinary, open-access journal is led by a distinguished editorial board composed of world-leading experts, at the forefront of disseminating cutting-edge research to researchers, scholars, clinicians, policymakers, and the public. Genetic research and the genomic basis of its impact on various biological processes are well-documented; however, many discoveries remain to be made. We are witnessing a new era of significant advancements in the understanding of genomic functions and variability, the use of genetic and genomic tools, and the analysis of the genetic basis of various biological phenomena.

《Frontiers in Genetics》发表经过严格同行评审的研究，涵盖与生命相关的所有领域的基因和基因组，从人类到植物，再到牲畜和其他模式生物。这本多学科、开放获取的期刊由世界领先的专家组成的杰出编辑委员会领导，致力于向研究人员、学者、临床医生、政策制定者和公众传播前沿研究。遗传研究及其对各种生物过程的影响的基因组有据可查，但仍有许多发现待探索。我们正处于一个新时代，见证基因组功能和变异性、遗传和基因组工具的使用，以及对各种生物现象的遗传基础分析方面的重大进展。

Category	Quartile
生物学	3
生物学, 遗传学	3

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