ABSTRACT Background The degree and time course of improvement in left ventricular (LV) function with treatment in patients with tachycardiomyopathy (TCMP) is highly variable. This study aims to clinically characterize the recovery of TCMP based on the extent and course of improvement in LV function and identify predictors of complete myocardial recovery. Methods In this prospective, single‐center, observational study, patients with suspected TCMP who underwent successful tachyarrhythmia termination/control were included. Clinical and echocardiographic assessment of LV function was done at baseline, within 1 h after tachyarrhythmia termination, 24 h later, and at 12 weeks follow‐up. Results Ninety‐nine patients were enrolled in the study. Six patients had immediate normalization of LV ejection fraction (LVEF) with reversion to sinus rhythm and were labeled as “pseudo‐TCMP”; the remaining 93 patients were included in the analysis. Based on complete versus partial normalization of LVEF at 12‐week follow‐up, 50 patients (53.8%) were labeled as completely recovered TCMP and 43 (46.2%) as partially recovered TCMP respectively. Causative arrhythmias included atrial fibrillation (38%), focal atrial tachycardia (28%), atrial flutter (22%), ventricular arrhythmias (11%), and orthodromic re‐entrant tachycardia (2%). The LVEF at presentation was 0.25 ± 0.05 which improved to 0.36 ± 0.11 within 1 h after tachycardia termination ( p &lt; 0.0001), 0.41 ± 0.14 24 h later ( p = 0.009) and to 0.52 ± 0.12 at 12 weeks follow‐up ( p &lt; 0.0001). Male gender was the only differentiating statistically significant variable between completely recovered and partially recovered TCMP, 24 (48%) versus 30 (69.7%) respectively ( p = 0.0339). Conclusion Nearly half of the TCMP patients have complete recovery of LV function at 12 weeks follow‐up, while the other half have a partial recovery only. There was no robust predictor of complete myocardial recovery.

Neeta Bachani

Harshad Shah

Raghav Bansal

Vijay Soorampally

Gopi Krishna Panicker

Yash Lokhandwala

Pacing and Clinical Electrophysiology

Pacing and Clinical Electrophysiology (PACE) is the foremost peer-reviewed journal in the field of pacing and implantable cardioversion defibrillation, publishing over 50% of all English language articles in its field, featuring original, review, and didactic papers, and case reports related to daily practice. Articles also include editorials, book reviews, Musings on humane topics relevant to medical practice, electrophysiology (EP) rounds, device rounds, and information concerning the quality of devices used in the practice of the specialty.

PACE - Pacing and Clinical Electrophysiology is the leading peer-reviewed journal in the field of pacing and implantable cardioversion defibrillation, publishing over 50% of all English language articles in this area. The journal features original research, reviews, didactic papers, and case reports relevant to daily practice. Additionally, it includes editorials, book reviews, reflections on humane topics related to medical practice, electrophysiology (EP) rounds, device rounds, and information regarding the quality of devices used in the specialty.

《PACE - Pacing and Clinical Electrophysiology》是心脏起搏和植入式心脏复律除颤领域的顶尖同行评审期刊，发表了该领域超过50%的英文文章。期刊内容包括原创研究、综述、教学论文和与日常实践相关的病例报告。此外，文章还包括社论、书评、与医学实践相关的人文主题思考、电生理（EP）讨论、设备讨论，以及有关该专业使用设备质量的信息。

Category	Quartile
医学	4
医学, 心脏和心血管系统	4
医学, 工程生物医学	4

Characterization of Myocardial Recovery in Patients With Tachycardiomyopathy

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Journal Info

Category	Quartile
ENGINEERING, BIOMEDICAL	3