New thiosemicarbazones were synthesized in excellent yield reaction of indole derivatives with thiosemicarbazides. These thiosemicarbazones were reacted with ethyl bromoacetate to produce original heterocyclic-substituted indole derivatives possessing a 4-oxo-thiazolidine group. Analytical IR and NMR spectra and elemental analysis were performed to reveal their structures. The antimicrobial activity of all synthesized compounds was evaluated for antibacterial activity in vitro against Gram-positive and Gram-negative bacteria. Antibacterial screening data showed that two compounds demonstrated activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. These preliminary results indicate that some of these newly synthesized compounds show a promising antibacterial potency.

Abdelmadjid Benmohammed

Nawel Rekiba

Yassine Sehanine

Ahmed Amine Louail

Omar Khoumeri

Mokhtaria Kadiri

Ayada Djafri

Thierry Terme

Patrice Vanelle

Monatshefte für Chemie - Chemical Monthly

"Monatshefte für Chemie/Chemical Monthly" was originally conceived as an Austrian journal of chemistry. It has evolved into an international journal covering all branches of chemistry. Featuring the most recent advances in research in analytical chemistry, biochemistry, inorganic, medicinal, organic, physical, structural, and theoretical chemistry, Chemical Monthly publishes refereed original papers and a section entitled "Short Communications". Reviews, symposia in print, and issues devoted to special fields will also be considered.

"Monatshefte für Chemie/Chemical Monthly" was originally established as an Austrian journal of chemistry and has since evolved into an international journal that covers all branches of chemistry. It features the latest research advancements in analytical chemistry, biochemistry, inorganic chemistry, medicinal chemistry, organic chemistry, physical chemistry, structural chemistry, and theoretical chemistry. Chemical Monthly publishes peer-reviewed original papers and includes a section titled "Short Communications." Reviews, printed symposia, and issues dedicated to special fields are also considered for publication.

《Monatshefte für Chemie/Chemical Monthly》最初是作为一本奥地利化学期刊而创办的，现已发展为一本国际性期刊，涵盖化学的各个分支。该期刊展示了分析化学、生物化学、无机化学、药物化学、有机化学、物理化学、结构化学和理论化学等领域的最新研究进展。Chemical Monthly发表经过同行评审的原创论文，并设有“短篇通讯”栏目。同时，期刊也会考虑发表综述文章、印刷研讨会以及专门领域的特刊。

Monatshefte fur Chemie

Synthesis and antimicrobial activities of new thiosemicarbazones and thiazolidinones in indole series

Preliminary results indicate that some of these newly synthesized compounds show a promising antibacterial potency.

Category	Quartile
化学	4
化学, 化学综合	4

Synthesis and antimicrobial activities of new thiosemicarbazones and thiazolidinones in indole series

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info

Category	Quartile
CHEMISTRY, MULTIDISCIPLINARY	3