Life expectancy has increased by three decades since the mid-twentieth century. Parallel healthspan expansion has however not followed, largely impeded by the pandemic of chronic diseases afflicting a growing older population. The lag in quality of life is a recognized challenge that calls for prioritization of disease-free longevity. Contemporary communal, clinical and research trends aspiring to extend the health horizon are here outlined in the context of an evolving epidemiology. A shared action integrating public and societal endeavors with emerging interventions that target age-related multimorbidity and frailty is needed. A multidimensional buildout of a curative perspective, boosted by modern anti-senescent and regenerative technology with augmented decision making, would require dedicated resources and cost-effective validation to responsibly bridge the healthspan-lifespan gap for a future of equitable global wellbeing.

Armin Garmany

Satsuki Yamada

Andre Terzic

npj Regenerative Medicine

NPJ REGENERATIVE MEDICINE 是一本新的开放获取、仅限在线的期刊，致力于发表最高质量的研究，以帮助人体修复、替换、恢复和再生受损组织和器官。

NPJ Regenerative Medicine is a new open-access, online-only journal dedicated to publishing high-quality research aimed at facilitating the repair, replacement, restoration, and regeneration of damaged tissues and organs in the human body.

NPJ Regenerative Medicine 是一本新的开放获取、仅限在线的期刊，专注于发表高质量的研究，旨在促进人体对受损组织和器官的修复、替换、恢复和再生。

Category	Quartile
医学	1
医学, 工程生物医学	1
医学, 细胞与组织工程	2

Longevity leap: mind the healthspan gap

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Journal Info

Category	Quartile
ENGINEERING, BIOMEDICAL	1