ABSTRACT Neurological manifestations of nonketotic hyperglycemia are frequently seen, with mainly symptoms of confusion or coma. While hyperglycemia-induced seizures are less common, isolated aphasic status epilepticus is very rare, difficult to diagnose, and may be unrecognized by clinicians. In this case report, a 51-year-old man who presented with confusion and incoherent speech for two weeks is discussed. He was diagnosed with nonketotic hyperglycemia, whose electroencephalography (EEG) findings were suggestive of isolated aphasic status epilepticus. His magnetic resonance imaging (MRI) of the brain showed subcortical T2/FLAIR hypointense lesions with cortical T2/FLAIR hyperintensities and restricted diffusion. Although this condition usually responds well to intensive insulin therapy and fluid replacement, many researchers found some persistent aphasic seizures that did not improve until the addition of anti-seizure medications (ASMs).

Jedsada Khieukhajee

Suphasit Seoratanaphunt

Krittima Asavaveeradech

Sunisa Hangsapruek

Dementia & Neuropsychologia

Dementia top Neuropsychologia the official scientific journal of the Cognitive Neurology and Ageing Department of the Brazilian Academy of Neurology and of the Brazilian Association of Geriatric Neuropsychiatry, is published by the "Associação Neurologia Cognitiva e do Comportamento", a nonprofit Brazilian association. Regularly published on March, June, September, and December since 2007.

Dementia e Neuropsychologia is the official scientific journal of the Cognitive Neurology and Ageing Department of the Brazilian Academy of Neurology and the Brazilian Association of Geriatric Neuropsychiatry. It is published by the non-profit Brazilian association "Associação Neurologia Cognitiva e do Comportamento". The journal has been regularly published in March, June, September, and December since 2007.

《Dementia e Neuropsychologia》是巴西神经病学学会的认知神经学与老龄化部门和巴西老年神经精神病学协会的官方科学期刊，由巴西非营利性协会"Associação Neurologia Cognitiva e do Comportamento"出版。自2007年起，该期刊定期于每年的3月、6月、9月和12月出版。

Hyperglycemia-induced isolated aphasic status epilepticus a case-report and literature review

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