Importance: Acne vulgaris is the most common skin condition affecting late adolescents across the globe. Although prior studies have evaluated epidemiologic patterns of acne vulgaris in various ethnicities and regions, adequate understanding of the worldwide burden of the disease associated with patients in their late adolescence (15–19-year olds) remains lacking. Objective: To assess the global burden of the disease associated with acne vulgaris for late adolescents (15–19-year olds) and provide an overview of the epidemiology, pathophysiology, and treatment options for acne in this population. Design: Database summary study. Setting: Global Burden of Disease Study 2010 database. Participants: Global Burden of Disease regions comprised countries with prevalence of acne vulgaris between the ages of 15 and 19 years. Main outcomes and measures: Geographic region-level disability-adjusted life year rates (per 100,000 persons) associated with acne vulgaris in years 1990 through 2010. Median percentage change in disability-adjusted life year rates was estimated for each region across the specified study period. Conclusion and relevance: Acne vulgaris-associated disease burden exhibits global distribution and has continued to grow in prevalence over time within this population. This continued growth suggests an unmet dermatologic need worldwide for this disorder and potential opportunities for improved access and delivery of dermatologic care. Our analysis of the literature reveals numerous opportunities for enhanced patient care. To that end, we highlight some of the effective and promising treatments currently available and address important factors, such as sex, nationality, genetics, pathophysiology, and diet, as they relate to acne vulgaris in late adolescence. Keywords: review, epidemiology, GBD, hormones, diet

Darren Lynn

Tamara Umari

Robert Dellavalle

Cory Dunnick

Adolescent Health Medicine and Therapeutics

Adolescent Health, Medicine and Therapeutics is an international, peer reviewed, open access journal focusing on health, pathology, and treatment issues specific to the adolescent age group, including health issues affecting young people with cancer. Original research, reports,  editorials, reviews,   commentaries and adolescent-focused clinical trial design  are welcomed.     All aspects of health maintenance, preventative measures,  disease treatment interventions, studies investigating the poor outcomes for some treatments in this group of patients,   and the challenges when transitioning from adolescent to adult care are addressed within the journal.     Practitioners from all disciplines are invited to submit their work as well as health care researchers and patient support groups.         Areas covered include:    Physical and mental development in the adolescent period,  Behavioral issues,  Pathologies and treatment interventions specific to this age group,  Prevalence and incidence studies,  Diet and nutrition,  Specific drug handling, efficacy, and safety issues,  Drug development programs,  Outcome studies, patient satisfaction, compliance, and adherence,  Patient and health education programs and studies.

Adolescent Health, Medicine and Therapeutics is an international, peer-reviewed, open-access journal that focuses on health, pathology, and treatment issues specific to the adolescent age group, including health concerns affecting young people with cancer. We welcome original research, reports, editorials, reviews, commentaries, and adolescent-focused clinical trial designs. The journal addresses all aspects of health maintenance, preventive measures, disease treatment interventions, studies investigating poor outcomes for some treatments in this patient group, and the challenges faced during the transition from adolescent to adult care. Practitioners from all disciplines, as well as healthcare researchers and patient support groups, are invited to submit their work. Areas covered include: physical and mental development during adolescence, behavioral issues, pathologies and treatment interventions specific to this age group, prevalence and incidence studies, diet and nutrition, specific drug handling, efficacy and safety issues, drug development programs, outcome studies, patient satisfaction, compliance and adherence, and patient and health education programs and studies.

《Adolescent Health, Medicine and Therapeutics》是一本国际性的、经过同行评审的开放获取期刊，专注于青少年群体特有的健康、病理和治疗问题，包括影响癌症青少年的健康问题。我们欢迎原创研究、报告、社论、综述、评论以及以青少年为中心的临床试验设计。期刊涵盖了健康维护、预防措施、疾病治疗干预、研究某些治疗在这一群体中不良结果的研究，以及青少年向成人护理过渡时面临的挑战。我们邀请各学科的从业者、医疗研究人员和患者支持团体提交他们的工作。期刊涉及的领域包括：青少年时期的身心发展、行为问题、特定于该年龄段的病理和治疗干预、流行病学和发生率研究、饮食和营养、特定药物的处理、疗效和安全性问题、药物开发项目、结果研究、患者满意度、依从性和遵循性、患者和健康教育项目及研究。

Adolescent Health, Medicine and Therapeutics

AHMT

The epidemiology of acne vulgaris in late adolescence

Assessment of the global burden of the disease associated with acne vulgaris for late adolescents (15–19-year olds) and an overview of the epidemiology, pathophysiology, and treatment options for acne in this population suggest an unmet dermatologic need worldwide for this disorder and potential opportunities for enhanced patient care.

The epidemiology of acne vulgaris in late adolescence

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