Benchtop NMR spectroscopy has known a major growth over the last decade, thanks to the design of permanent, compact magnets in the 1-2 T range, that provide remarkable performance in terms of resolution and sensitivity. Although resulting spectra are more limited than their high-field counterparts, the achievable structural and quantitative information can be maximized by a clever use of pulse sequences -in particular those involving gradient pulses -and by advanced data processing algorithms. In this chapter, we describe the main characteristics of benchtop NMR spectroscopy in 2020, both in terms of hardware and typical performance. We highlight the most recent methodological improvements in the field, in terms of pulse sequences, hyperpolarization and data processing, which have significantly improved the resolution and sensitivity of benchtop NMR spectrometers. Finally, we discuss major applications of benchtop NMR spectroscopy, for reaction and process monitoring, but also for quality control and profiling. The number of papers in this field in the last few years undoubtedly highlights the major role that benchtop NMR has to play for applications in areas such as food and pharmaceutical industry, flow chemistry, and profiling of complex samples.

Thomas Castaing-Cordier

Dylan Bouillaud

Jonathan Farjon

Patrick Giraudeau

Annual Reports on NMR Spectroscopy

核磁共振光谱年度报告是专家和非专家熟悉核磁共振光谱新技术和应用的首要手段。本系列还介绍了磁共振成像 (MRI) 研究的最新进展。对于有机、无机、分析和物理化学家、生物化学家、结构生物学家、物理学家以及所有研究和使用 NMR 光谱学的人来说，这是一个宝贵的资源。

The Annual Reports on NMR Spectroscopy serves as a vital resource for both experts and non-experts to familiarize themselves with the latest techniques and applications in nuclear magnetic resonance spectroscopy. This series also covers recent advancements in magnetic resonance imaging (MRI) research. It is an invaluable reference for organic, inorganic, analytical, and physical chemists, biochemists, structural biologists, physicists, and anyone involved in the research and application of NMR spectroscopy.

《Annual Reports on NMR Spectroscopy》是专家和非专家了解核磁共振光谱新技术与应用的重要资源。本系列还涵盖了磁共振成像（MRI）研究的最新进展。对于有机、无机、分析和物理化学家、生物化学家、结构生物学家、物理学家以及所有研究和使用NMR光谱学的人员来说，这是一份极具价值的参考资料。

Category	Quartile
化学	3
化学, 光谱学	3

Recent advances in benchtop NMR spectroscopy and its applications

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