Abstract Aims Bipolar disorders are clinically complex, chronic and recurrent disorders. Few treatment options are effective across hypomanic, manic, depressive and mixed states and as continuation or maintenance treatment after initial symptom remission. The aim of this review was to provide an up‐to‐date overview of research on the efficacy, tolerability and cognitive effects of electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), magnetic seizure therapy (MST), deep brain stimulation (DBS) and vagus nerve stimulation (VNS). Methods References included in this review were identified through multiple searches of the Embase, PubMed / MEDLINE and APA PsycINFO electronic databases for articles published from inception until February 2022. Published reviews, meta‐analyses, randomised controlled trials and recent studies were prioritised to provide a comprehensive and up‐to‐date overview of research on brain stimulation in patients with bipolar disorders. Results The evidence base for brain stimulation as an add‐on or alternative to pharmacological and psychological treatments in patients with bipolar disorders is limited but rapidly expanding. Brain stimulation treatments represent an opportunity to treat all bipolar disorder states, including cognitive dysfunction during euthymic periods. Conclusion Whilst findings to date have been encouraging, larger randomised controlled trials with long‐term follow‐up are needed to clarify important questions regarding treatment efficacy and tolerability, the frequency of treatment‐emergent affective switches and effects on cognitive function.

Julian Mutz

Bipolar Disorders

BIPOLAR DISORDERS 是一本国际期刊，发表与双相情感障碍和相关疾病的基本机制、临床方面或治疗相关的所有研究。它旨在为该领域的新研究提供一个单一的国际渠道，并涵盖以下领域的研究： 生物化学生理学神经精神药理学神经解剖神经病理学遗传学脑成像流行病学现象学双相情感障碍的临床方面和治疗双相情感障碍还包含形成这些疾病的新治疗策略发展的论文以及关于分裂情感障碍和抑郁障碍的主题，因为这些可能是与双相情感障碍重叠领域的循环障碍。该杂志将考虑在以下领域提交出版物：观点、研究文章、通信、临床角和思考。其中有多种类型的文章：特邀社论、辩论、评论文章、原创文章、评论、致编辑的信、临床难题、临床好奇心、临床护理和沉思。

Bipolar Disorders is an international journal that focuses on the fundamental mechanisms, clinical aspects, and treatment of bipolar disorder and related conditions. The journal aims to provide a single international channel for new research in the field, covering studies in the following areas: biochemistry, physiology, neuropsychopharmacology, neuroanatomy, neuropathology, genetics, brain imaging, epidemiology, phenomenology, as well as the clinical aspects and treatment of bipolar disorder. Additionally, the journal welcomes papers on new therapeutic strategies for these disorders, as well as topics related to schizoaffective disorder and depressive disorders, as these may overlap with bipolar disorder. The journal considers submissions in various formats, including viewpoints, research articles, communications, clinical corners, and reflections. There are multiple types of articles: invited editorials, debates, review articles, original research, letters to the editor, clinical dilemmas, clinical curiosities, clinical care, and reflections.

《Bipolar Disorders》是一本国际期刊，专注于双相情感障碍及相关疾病的基本机制、临床特征和治疗研究。该期刊旨在为该领域的新研究提供一个国际平台，涵盖以下研究领域：生物化学、生理学、神经精神药理学、神经解剖学、神经病理学、遗传学、脑成像、流行病学、现象学，以及双相情感障碍的临床特征和治疗。此外，期刊还欢迎关于新治疗策略的论文，以及与分裂情感障碍和抑郁障碍相关的研究，因为这些领域可能与双相情感障碍存在重叠。该期刊接受多种类型的投稿，包括观点文章、研究论文、通信、临床案例和思考。文章类型包括特邀社论、辩论、评论、原创研究、书信、临床难题、临床好奇心、临床护理和沉思。

Brain stimulation treatment for bipolar disorder

The aim of this review was to provide an up‐to‐date overview of research on the efficacy, tolerability and cognitive effects of electroconvulsive therapy, transcranial magnetic stimulation, transranial direct current stimulation (tDCS), magnetic seizure therapy (MST), deep brain stimulation (DBS) and vagus nerve stimulation (VNS).

Category	Quartile
医学	2
医学, 临床神经病学	2
医学, 神经科学	2
医学, 精神病学	2

Brain stimulation treatment for bipolar disorder

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