Chitin is a polymer of N-acetyl glucosamine that forms the protective exoskeleton of all arthropods and is replaced periodically during growth and development. Chitin biosynthesis starts with the disaccharide trehalose, culminating in the polymerization of the N-acetyl glucosamine subunits by chitin synthase to produce chitin microfibrils. Chitin in the old exoskeleton is degraded by chitinases, deacetylases and hexosaminidases and recycled. Chitin synthesis has been used as a target for developing biorational insecticides such as benzoylphenyl ureas, diflubenzuron being the original such compound. Several benzoylphenyl ureas with diverse activity spectra have since been synthesized and widely used for pest control. Newer pesticides targeting not only chitinase and chitin synthase but also other novel sites are being developed. Understanding the various nuances of chitin metabolism and regulation with all the genomic resources on hand will undoubtedly pave the way for developing more target-oriented softer control agents that have minimal impact on the environment.

Daniel Doucet

Arthur Retnakaran

Insect Growth Disruptors

昆虫生理学进展对昆虫生理学的所有关键方面进行了全面而深入的评论。它是无脊椎动物生理学家、神经生物学家、昆虫学家、动物学家和昆虫生化学家的重要参考资料。

Advances in Insect Physiology provides comprehensive and in-depth reviews of all key aspects of insect physiology. It serves as an essential reference for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect biochemists.

《Advances in Insect Physiology》对昆虫生理学的各个关键方面进行了全面而深入的评论，是无脊椎动物生理学家、神经生物学家、昆虫学家、动物学家和昆虫生化学家的重要参考资料。

Category	Quartile
农林科学	2
农林科学, 昆虫学	2

Insect Chitin

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