Forces are increasingly recognized as major regulators of cell structure and function, and the mechanical properties of cells are essential to the mechanisms by which cells sense forces, transmit them to the cell interior or to other cells, and transduce them into chemical signals that impact a spectrum of cellular responses. Comparison of the mechanical properties of intact cells with those of the purified cytoskeletal biopolymers that are thought to dominate their elasticity reveal the extent to which the studies of purified systems can account for the mechanical properties of the much more heterogeneous and complex cell. This review summarizes selected aspects of current work on cell mechanics with an emphasis on the structures that are activated in cell-cell contacts, that regulate ion flow across the plasma membrane, and that may sense fluid flow that produces low levels of shear stress.

Paul A. Janmey

Christopher A. McCulloch

Annual Review of Biomedical Engineering

自 1999 年出版的《生物医学工程年度回顾》涵盖了生物医学工程广泛领域的重大发展，包括生物力学、生物材料、计算基因组学和蛋白质组学、组织工程、生物监测、医疗保健工程、药物输送、生物电工程、生化工程和生物医学成像主题。

The Annual Review of Biomedical Engineering, published since 1999, covers significant developments across a wide range of topics in biomedical engineering, including biomechanics, biomaterials, computational genomics and proteomics, tissue engineering, biosensing, healthcare engineering, drug delivery, bioelectrical engineering, biochemical engineering, and biomedical imaging.

《Annual Review of Biomedical Engineering》自1999年出版，涵盖了生物医学工程领域的多个重要主题，包括生物力学、生物材料、计算基因组学与蛋白质组学、组织工程、生物监测、医疗工程、药物输送、生物电工程、生化工程以及生物医学成像等。

Annu. Rev. Biomed. Eng.

Cell Mechanics: Integrating Cell Responses to Mechanical Stimuli

This review summarizes selected aspects of current work on cell mechanics with an emphasis on the structures that are activated in cell-cell contacts, that regulate ion flow across the plasma membrane, and that may sense fluid flow that produces low levels of shear stress.

Category	Quartile
工程技术	1
工程技术, 工程生物医学	1

Cell Mechanics: Integrating Cell Responses to Mechanical Stimuli

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info

Category	Quartile
ENGINEERING, BIOMEDICAL	1