Contents 1. Introduction 2. Biological functions of PFKP 2.1 PFKP in cell growth and proliferation 2.2 PFKP in cell apoptosis/survival 2.3 PFKP in autophagy 2.4 PFKP in cell migration and metastasis 2.5 PFKP in stemness and tumor immune microenvironment 3. PFKP functions at various cellular locations 3.1 Cell membrane 3.2 Mitochondrion 3.3 Lysosomal membrane 3.4 Nucleus 4. PFKP in immune cells 4.1 PFKP in T cells and dendritic cells 4.2 PFKP expressed in multiple immune cells 5. The regulation of PFKP expression 6. The regulation of PFKP activity 7. Prognostic value of PFKP and strategies to target PFKP for cancer therapy 7.1 Prognostic value of PFKP 7.2 Strategies to target PFKP for cancer therapy 8. Conclusion and future directions Acknowledgments References

Haizhen Wang

Tiffany Penaloza

Amanda J. Manea

Xueliang Gao

Advances in Cancer Research

癌症研究进展 (ACR) 涵盖了一段非凡的发现时期，其中包括生物学革命的开始。癌症研究进展 (ACR) 涵盖了一段非凡的发现时期，其中包括生物学革命的开始。第一本 ACR 卷出版于 WATSON 和 CRICK 报道生物学中心法则 DNA 双螺旋的那一年。在前 100 卷中，发现了一些帮助塑造这场革命的人的许多贡献，他们在癌症研究中取得了许多显着的发现，并由此发展而来。

Advances in Cancer Research covers significant advancements in the field of cancer research, marking the beginning of a biological revolution. The first volume was published in the same year that Watson and Crick reported the double helix structure of DNA. In the first 100 volumes, numerous contributions from scientists who shaped this revolution led to significant discoveries in cancer research, driving the development of the field.

《Advances in Cancer Research》涵盖了癌症研究领域的重大进展，标志着生物学革命的开端。第一卷的出版恰逢沃森和克里克报道DNA双螺旋结构的那一年。在前100卷中，许多为这场革命做出贡献的科学家们在癌症研究中取得了显著的发现，这些发现推动了该领域的发展。

Category	Quartile
医学	2
医学, 肿瘤学	3

PFKP: More than phosphofructokinase

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