Blood oxygenation-level dependent cerebrovascular reactivity (BOLD-CVR) has gained attention in recent years as an effective way to investigate CVR, a measure of the hemodynamic state of the brain, with high spatial and temporal resolution. An association between impaired CVR and diverse pathologies has been observed, especially in ischemic cerebrovascular diseases and brain gliomas. The ability to obtain this information intraoperatively is novel and has not been widely tested. We report our first experience with this intraoperative technique in vascular and oncologic neurosurgical patients, discuss the results of its feasibility, and the possible developments of the intraoperative employment of BOLD-CVR.

Giovanni Muscas

Christiaan Hendrik Bas van Niftrik

Martina Sebök

Giuseppe Esposito

Luca Regli

Jorn Fierstra

Acta Neurochirurgica Supplement

In addition to the regular journal, "Acta Neurochirurgica" publishes 3-4 supplement volumes per year. These comprise proceedings of international meetings or other material of general neurosurgical interest.

In addition to the regular journal, "Acta Neurochirurgica", the supplement publishes 3-4 volumes per year. These volumes include proceedings from international meetings and other materials of general interest in neurosurgery.

《Acta Neurochirurgica, Supplementum》是《Acta Neurochirurgica》期刊的补充刊物，每年出版3-4卷。这些补充卷包含国际会议的会议记录或其他与神经外科相关的一般性材料。

Intraoperative BOLD-fMRI Cerebrovascular Reactivity Assessment

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