Some characteristics of silica-based materials, such as the control/adjustment of their physical and chemical properties, compatibility, and friendly-use synthesis methods, have held the attention of several scientific groups over the years. This condition of prominence becomes even more evident when we seek these characteristics at the micro- and/or nanoscale. Among existing methods to obtain these micro/nanomaterials, the Stöber method is the focus of this review. This method is known to enable the production of silica micro- or nanoparticles from reagents of medium-easy manipulation under mild conditions using equipment that is common in most laboratories. However, this method has many nuances that must be considered to guarantee accurate results, either in size or distribution, and to ensure result reproducibility. Thus, in this review, we discuss the effects of the primary components used in the synthesis of these materials (i.e., TEOS, ammonia, and water), as well as those of other reaction conditions, such as solvent, temperature, and ionic strength. Therefore, we discuss studies involving the synthesis and characterization of micro- and nanoparticles over the years to establish discussions between their experimental observations and proposed models. This review provides experimental observations about the synthesis of these materials, as well as discussions according to complementary and/or contradictory evidence found over the years. This review seeks to help those who intend to work with this method and provide certain key points that, in our experience, can be important to obtain desired results.

Alan Dos Santos da Silva

João Henrique Zimnoch Dos Santos

Advances in colloid and interface science

胶体和界面科学领域内任何主题的评论文章都将被视为适合该期刊。该主题应作为对该主题领域当前状态的批判性评论进行深入处理，包括作者对该主题的知情意见。手稿应比较和对比评论文献中的想法；并处理所讨论的想法的局限性。因此，该期刊中的文章通常由公认的专家撰写。

This journal welcomes review articles on any topic within the field of colloid and interface science. The articles should provide an in-depth examination of the current state of the field, along with the author's informed opinions. Manuscripts should compare and contrast ideas presented in the literature and address the limitations of the discussed concepts. As a result, articles in this journal are typically authored by recognized experts in the field.

本期刊欢迎关于胶体和界面科学领域的任何主题的评论文章。文章应深入探讨该领域的当前状态，并提供作者的专业见解。手稿应比较和对比现有文献中的观点，并讨论所涉及观点的局限性。因此，本期刊的文章通常由该领域的公认专家撰写。

Category	Quartile
化学	1
化学, 物理化学	1

Stöber method and its nuances over the years.

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Journal Info

Category	Quartile
CHEMISTRY, PHYSICAL	1