There are very few Spanish studies that compare oncological outcomes following radical prostatectomy (RP) based on surgical approach, and their methodology is not appropriate.To compare oncological outcomes in terms of surgical margins (SM) and biochemical recurrence (BR) between open radical prostatectomy (ORP) and laparoscopic radical prostatectomy (LRP).Comparison of two cohorts (307 with ORP and 194 with LRP) between 2007-2015. Surgical margin status was defined as positive or negative, and BR as a PSA rise of >0.4 ng/ml after surgery. To compare the qualitative variables, we employed the Chi-squared test, and ANOVA was used for quantitative variables. We performed a multivariate analysis using logistic regression to evaluate the predictive factors of SM, and a multivariate analysis using Cox regression to evaluate the predictive factors of BR.Gleason 7 (3+4) was determined in the surgical specimens of 43.5% of patients, and 31.7% had positive SM. The most frequent pathological stage was pT2c, on the 61.9% of the cases. No significant differences were found between both groups, except for extracapsular extension (p=0.001), more frequent in LRP. The median follow-up was 49 months. BR was seen in the 23% of patients, without significant differences between groups. In the multivariable analysis, only the D'Amico risk group behaved as an independent predictive factor of positive SM, and Gleason score and positive SM acted as independent predictive factors of BR.The surgical approach did not influence SM status or BR.

E. Martínez-Holguín

F. Herranz-Amo

J. Mayor de Castro

L. Polanco-Pujol

J. Hernández-Cavieres

D. Subirá-Ríos

M.I. Moralejo-Gárate

J. Aragón-Chamizo

C. Hernández-Fernández

Actas Urológicas Españolas

ACTAS UROLÓGICAS ESPAÑOLAS 是一本致力于泌尿系统疾病和肾移植的国际期刊。自 1974 年以来一直是西班牙泌尿外科协会的官方出版物，自 2008 年以来一直是美国泌尿外科联合会的官方出版物。其文章涵盖与泌尿外科相关的所有方面。ACTAS UROLÓGICAS ESPAÑOLAS，由同行评审系统（双盲）管理，在线发表于西班牙语和英语。因此，可以以西班牙语或英语发送手稿，并将提供双向免费翻译。

Actas Urológicas Españolas is an international journal dedicated to diseases of the urinary system and kidney transplantation. Since its inception in 1974, it has served as the official publication of the Spanish Urological Association and, since 2008, as the official journal of the American Urological Association. The articles published cover all aspects related to urology and are managed through a double-blind peer review system. The journal is published online in both Spanish and English, allowing submissions in either language and offering free bidirectional translation services.

《Actas Urológicas Españolas》是一本专注于泌尿系统疾病和肾移植的国际期刊。自1974年起，它一直是西班牙泌尿外科协会的官方出版物，并自2008年起成为美国泌尿外科联合会的官方期刊。期刊的文章涵盖泌尿外科的各个方面，采用双盲同行评审制度。该期刊在线发布，提供西班牙语和英语两种语言的文章投稿服务，并为作者提供双向免费翻译。

Actas Urologicas Espanolas

Comparación entre prostatectomía laparoscópica y abierta: análisis de la evolución oncológica

The surgical approach did not influence SM status or BR, and only the D'Amico risk group behaved as an independent predictive factor of positive SM, and Gleason score and positive SM acted as independent predictive factors of BR.

Category	Quartile
医学	4
医学, 泌尿学与肾脏学	4

Comparación entre prostatectomía laparoscópica y abierta: análisis de la evolución oncológica

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Journal Info

Category	Quartile
UROLOGY & NEPHROLOGY	3