Dendrowardol C (1)-a novel sesquiterpenoid, with an unprecedented 4/5/6/6 tetracyclic carbon backbone, together with two known cyclopacamphane-type sesquiterpenoids; dendronobilin I (2) and dendrobane A (3) were isolated from the stems of Dendrobium wardianum Warner. The structure of 1 was established on the basis of spectroscopic data and the absolute configuration was determined by single-crystal X-ray diffraction crystallography. The hypothetical biosynthetic pathway of 1 was postulated. Compound 1 showed no cytotoxic activity against human tumor cell lines HL-60, SMMC-7721, A-549, MCF-7, and SW480.

Wei-Wei Fan

Feng-Qing Xu

Fa-Wu Dong

Xiao-Nian Li

Yan Li

Yu-Qing Liu

Jun Zhou

Jiang-Miao Hu

Natural Products and Bioprospecting

Nat. Prod. Bioprospect.

Dendrowardol C, a novel sesquiterpenoid from Dendrobium wardianum Warner

石斛烷醇C：一种来自石斛属植物沃氏石斛的新型倍半萜

Category	Quartile
化学	3
化学, 药物化学	3

Dendrowardol C, a novel sesquiterpenoid from Dendrobium wardianum Warner

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info

Category	Quartile
CHEMISTRY, MEDICINAL	1