The SARS-CoV-2 virus is the pathogenic agent of the COVID-19 disease, which pandemic had caused 6.8 million deaths worldwide by February 2023. In the course of the disease, involvement of the thyroid gland is observed. The pathomechanism of damage to the thyroid gland is bidirectional – direct cytotoxicity of the virus and the indirect effect of a cytokine storm. Circulating pro-inflammatory cytokines lead to deiodinase activity dysregulation, resulting in changes in plasma concentrations of TSH, fT3, and fT4. These hormone abnormalities are observed in about 16% of patients during COVID-19 and may also result from the treatment itself – systemic corticosteroids. Dysregulation of the immune system also leads to autoinflammatory thyroid diseases. It seems crucial to monitor thyroid hormones to detect subclinical forms of thyroiditis early. This paper presents the prevalence and potential pathomechanism of thyroid disorders observed during SARS-CoV-2 infection – subacute thyroiditis, low T3 syndrome, Graves-Basedow disease, and Hashimoto’s disease.

Agnieszka RABIZA

Anna SŁOWIŃSKA

Paweł GŁUSZAK

Katarzyna WINKEL

Julia KURZYCA

Maciej OWECKI

Postępy Biologii Komórki

POSTĘPY BIOLOGII KOMÓRKI (PBK) drukują artykuły przeglądowe w języku polskim lub angielskim z zakresu najnowszych osiągnięć biologii komórki, niepublikowane dotąd w innych wydawnictwach. Autorzy odpowiadają za ścisłość podawanych informacji. Obowiązuje terminologia zgodna z polskim mianownictwem biochemicznym, histologicznym, anatomicznym i embriologicznym oraz Słownikiem Biologii Komórki PAU 2008. Artykuły drukowane w PBK bez zgody redakcji nie mogą być publikowane w innych periodykach.

The journal "Advances in Cell Biology" (POSTĘPY BIOLOGII KOMÓRKI, PBK) publishes review articles in Polish or English on the latest achievements in cell biology that have not been previously published in other outlets. Authors are responsible for the accuracy of the information provided. The terminology used must comply with the Polish nomenclature in biochemistry, histology, anatomy, and embryology, as well as the 2008 PAU Dictionary of Cell Biology. Articles published in PBK cannot be published in other periodicals without the consent of the editorial board.

《Advances in Cell Biology》期刊（POSTĘPY BIOLOGII KOMÓRKI，PBK）发表关于细胞生物学最新进展的综述文章，文章可用波兰语或英语撰写，且未曾在其他出版物上发表。作者需对所提供信息的准确性负责。期刊使用的术语应符合波兰生物化学、组织学、解剖学和胚胎学的命名规范，以及2008年PAU细胞生物学词典的标准。未经编辑部同意，PBK上发表的文章不得在其他期刊上发布。

Category	Quartile
生物学	4
生物学, 细胞生物学	4

IMPACT OF SARS-CoV-2 INFECTION ON THYROID FUNCTION – PATOMECHANISM AND CLINICAL IMPLICATIONS

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Journal Info

Category	Quartile
CELL BIOLOGY	4