Laser-assisted drug delivery (LADD) is an emerging and rapidly evolving approach to the treatment of a variety of conditions including benign and malignant neoplasms, photoaging, pigmentary disorders , scar revision, and topical anesthesia . In LADD, a laser-induced zone of thermal damage (or microscopic ablation zone) renders the skin more vulnerable to topically applied medications, enhancing their absorption and optimizing their results. This article discusses the clinical evidence behind LADD, as well as proper patient selection, preparation, and appropriate surgical technique to safely and effectively perform LADD.

Jessica G. Labadie

Laser-Assisted Drug Delivery

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