In the natural world, animals make decisions on an ongoing basis, continuously selecting which action to undertake next. In the lab, however, the neural bases of decision processes have mostly been studied using artificial trial structures. New experimental tools based on the genetic toolkit of model organisms now make it experimentally feasible to monitor and manipulate neural activity in small subsets of neurons during naturalistic behaviors. We thus propose a new approach to investigating decision processes, termed reverse neuroethology. In this approach, experimenters select animal models based on experimental accessibility and then utilize cutting-edge tools such as connectomes and genetically encoded reagents to analyze the flow of information through an animal's nervous system during naturalistic choice behaviors. We describe how the reverse neuroethology strategy has been applied to understand the neural underpinnings of innate, rapid decision making, with a focus on defensive behavioral choices in the vinegar fly

Samuel K. Asinof

Gwyneth M. Card

Annual Review of Neuroscience

自 1978 年出版的《神经科学年度回顾》涵盖了整个神经科学领域的重大发展，包括分子和细胞神经科学、神经遗传学、发育、可塑性和修复、系统神经科学、认知神经科学、行为和疾病的神经生物学，以及偶尔回顾一下神经科学和伦理学的历史。

The Annual Review of Neuroscience, published since 1978, covers significant developments across the field of neuroscience, including molecular and cellular neuroscience, neurogenetics, development, plasticity and repair, systems neuroscience, cognitive neuroscience, the neurobiology of behavior and disease, and occasionally reviews the history of neuroscience and ethics.

《Annual Review of Neuroscience》自1978年出版，涵盖了神经科学领域的重大进展，包括分子和细胞神经科学、神经遗传学、发育、可塑性与修复、系统神经科学、认知神经科学、行为与疾病的神经生物学，以及偶尔回顾神经科学与伦理学的历史。

Category	Quartile
医学	1
医学, 神经科学	1

Neural Control of Naturalistic Behavior Choices

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