The activity patterns of grid cells form distinctively regular triangular lattices over the explored spatial environment and are largely invariant to visual stimuli, animal movement, and environment geometry. These neurons present numerous fascinating challenges to the curious (neuro)scientist: What are the circuit mechanisms responsible for creating spatially periodic activity patterns from the monotonic input-output responses of single neurons? How and why does the brain encode a local, nonperiodic variable—the allocentric position of the animal—with a periodic, nonlocal code? And, are grid cells truly specialized for spatial computations? Otherwise, what is their role in general cognition more broadly? We review efforts in uncovering the mechanisms and functional properties of grid cells, highlighting recent progress in the experimental validation of mechanistic grid cell models, and discuss the coding properties and functional advantages of the grid code as suggested by continuous attractor network models of grid cells.

Ling L. Dong

Ila R. Fiete

Annual Review of Neuroscience

自 1978 年出版的《神经科学年度回顾》涵盖了整个神经科学领域的重大发展，包括分子和细胞神经科学、神经遗传学、发育、可塑性和修复、系统神经科学、认知神经科学、行为和疾病的神经生物学，以及偶尔回顾一下神经科学和伦理学的历史。

The Annual Review of Neuroscience, published since 1978, covers significant developments across the field of neuroscience, including molecular and cellular neuroscience, neurogenetics, development, plasticity and repair, systems neuroscience, cognitive neuroscience, the neurobiology of behavior and disease, and occasionally reviews the history of neuroscience and ethics.

《Annual Review of Neuroscience》自1978年出版，涵盖了神经科学领域的重大进展，包括分子和细胞神经科学、神经遗传学、发育、可塑性与修复、系统神经科学、认知神经科学、行为与疾病的神经生物学，以及偶尔回顾神经科学与伦理学的历史。

Category	Quartile
医学	1
医学, 神经科学	1

Grid Cells in Cognition: Mechanisms and Function

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