The water-based combination of two inorganic chemical compounds such as sodium tungstate dihydrate-Na2WO4 × 2H2O and Aluminum sulfate octadecahydrate-Al2 (SO4) 3 × 18H2O that we have conditionally named 'Vomifal' has a broad antiviral activity in various DNA and RNA viruses, including Human Herpes Virus (HHV), African Swine Fever Virus (ASFV), Vaccinia Virus (VV), Hepatitis C Virus (HCV), Foot and Mouth Disease Virus (FMDV), Influenza A virus (A/Aichi/2/68 (H3N2)). In vitro and In vivo assays in several tissue cultures as well as in laboratory animals, conformed 'Vomifal' has a very low toxicity and the antiviral properties partially are due to its ability to induce gamma-IFN. Based on the results obtained, we can assume the presence of at least two mechanisms of the antiviral action of the studied drug. First or early stage - an unknown mechanism, possibly related to the effect on cellular receptors. Second or late stage - main antiviral properties probably associated with an interferonogenic effect.

Hranush Avagyan

Anaida Mirzoyan

Ferdinand Mirzoyan

Roza Izmailyan

Sona Hakobyan

Henry Voskanyan

Zara Semerjyan

Aida Avetisyan

Hranush Arzumanyan

Elena Karalova

Liana Abroyan

Lina Hakobyan

Nane Bayramyan

Nazeli Gevorgyan

Alexander Karalyan

Zaven Karalyan

Antiviral chemistry & chemotherapy

Antiviral Chemistry & Chemotherapy publishes the results of original research concerned with the biochemistry, mode of action, chemistry, pharmacology and virology of antiviral compounds. Manuscripts dealing with molecular biology, animal models and vaccines are welcome.     The journal also publishes reviews, pointers, short communications and correspondence.

Antiviral Chemistry and Chemotherapy publishes original research results related to the biochemistry, mode of action, chemistry, pharmacology, and virology of antiviral compounds. Manuscripts addressing molecular biology, animal models, and vaccines are also welcome. The journal additionally publishes reviews, pointers, short communications, and correspondence.

《Antiviral Chemistry and Chemotherapy》期刊致力于发表与抗病毒化合物的生物化学、作用机制、化学、药理学和病毒学相关的原创研究成果。欢迎提交涉及分子生物学、动物模型和疫苗的手稿。此外，期刊还接受综述、指引、简短通讯和信函的投稿。

Antiviral Chemistry and Chemotherapy

New composition of tungsten has a broad range of antiviral activity

钨的新成分具有广泛的抗病毒活性

New composition of tungsten has a broad range of antiviral activity

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