Recent developments in preparatory procedures for electron microscopy and immunocytochemistry are presented as a background for the morphological diagnosis of bone dysplasia. With the new low temperature embedding techniques and the availability of monoclonal antibodies raised against the main matrix macromolecules, biopsies have proved to be an important complement to clinical and radiological workup and they may sometimes provide the final clue to the diagnosis.

BENGT ENGFELDT

BRUCE CATERSON

OLE EKLÖF

KJELL HULTENBY

ULTRASTRUCTURE OF HYALINE CARTILAGE

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