Abstract Currently, only a few theoretical support systems exist for the treatment of hyperthyroidism. They are typically not practically applicable and solely focus on Graves’ disease. The recently developed DigiThy software framework can be used to assist physicians for methimazole dose titration during the treatment of Graves’ disease. In this study, a pool of 60 virtual patients was created to compare physicians’ individual treatment approaches by 8 different physicians and students (including three colleagues, unexperienced with care of Graves’ disease) with the decision support system DigiThy in terms of already defined performance indices. These indices are used to assess the deviation of FT4 from the reference range throughout the treatment. The computer aided treatment algorithms outperformed the usual care approach according to different prespecified criteria for treatment success. Two out of the three unexperienced colleagues improved their treatment success over time, i.e. with more patients treated. In conclusion, our findings suggest that the DigiThy software may be a useful tool for use as a decision support system in routine care of patients with Graves’ disease, while also serving as an effective training tool for the education of physicians. Randomized controlled studies are required before implementation of DigiThy in daily clinical practice.

Thomas Benninger

Verena Theiler-Schwetz

Stefan Pilz

Christian Trummer

Markus Reichhartinger

Journal für Klinische Endokrinologie und Stoffwechsel

Das Journal für Klinische Endokrinologie und Stoffwechsel veröffentlicht Originalarbeiten, Übersichten, Fallberichte, Kurzberichte sowie Kommentare aus allen Bereichen der Endokrinologie und Stoffwechselerkrankungen. Experimentelle Untersuchungen sollen einen direkten klinischen Bezug aufweisen. Das Journal versteht sich als praxisorientiertes Fortbildungsmagazin und möchte Aktualität und Wissen vermitteln. Namhafte Expert*innen kommen zu Wort und beleuchten Schwerpunkte des Praxisalltags. Dadurch soll die Einbindung neuester Erkenntnisse in die tägliche Routinearbeit erleichtert werden.

The Austrian Journal of Clinical Endocrinology and Metabolism is dedicated to the field of clinical endocrinology and metabolism, publishing original research, review articles, case reports, short communications, and commentaries. Experimental studies are expected to have a direct clinical relevance, aiming to provide practical continuing education resources for clinicians and convey the latest knowledge and information. Renowned experts contribute their insights, focusing on key issues in everyday practice, thereby assisting clinicians in integrating the latest research findings into their daily work.

《Austrian Journal of Clinical Endocrinology and Metabolism》是一本专注于临床内分泌学和代谢领域的期刊，发布原创研究、综述文章、病例报告、短篇报道以及评论。期刊中的实验研究需与临床实践密切相关，旨在为临床工作者提供实用的继续教育资源，传递最新的知识和信息。众多知名专家在此分享他们的见解，聚焦于日常实践中的关键问题，从而帮助临床医生更好地将最新研究成果融入日常工作中。

Hyperthyroidism therapy: What can decision support systems already achieve?

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Journal Info

Category	Quartile
ENDOCRINOLOGY & METABOLISM	4