Hyalocytes are sentinel macrophages residing within the posterior vitreous cortex anterior to the retinal inner limiting membrane (ILM). Following anomalous PVD and vitreoschisis, hyalocytes contribute to paucicellular (vitreo-macular traction syndrome, macular holes) and hypercellular (macular pucker, proliferative vitreo-retinopathy, proliferative diabetic vitreo-retinopathy) diseases.

Charlotte H. Jones

Wei Gui

Ricarda G. Schumann

Stefaniya K. Boneva

Clemens A. K. Lange

Koen A. van Overdam

Toco Y. P. Chui

Richard B. Rosen

Michael Engelbert

J. Sebag

Expert Review of Ophthalmology

The worldwide problem of visual impairment is set to increase, as we are seeing increased longevity in developed countries. This will produce a crisis in vision care unless concerted action is taken.     The substantial value that ophthalmic interventions confer to patients with eye diseases has led to intense research efforts in this area in recent years, with corresponding improvements in treatment, ophthalmic instrumentation and surgical techniques. As a result, the future for ophthalmology holds great promise as further exciting and innovative developments unfold.

The global issue of visual impairment is expected to worsen as life expectancy increases in developed countries. This could lead to a crisis in vision care unless coordinated action is taken. The significant value that ophthalmic interventions provide to patients with eye diseases has spurred intense research efforts in this field in recent years, resulting in corresponding improvements in treatment, ophthalmic instrumentation, and surgical techniques. Consequently, the future of ophthalmology holds great promise as exciting and innovative developments continue to unfold.

随着发达国家人均寿命的延长，全球视觉障碍问题将日益严重。如果不采取协调一致的行动，这将导致视觉护理危机。近年来，眼科干预措施为眼病患者带来的显著价值，促使了该领域的深入研究，相关的治疗、眼科仪器和外科技术也得到了相应的改善。因此，眼科学的未来充满希望，随着更多令人兴奋和创新的发展不断涌现。

Hyalocytes in proliferative vitreo-retinal diseases

Hyalocytes are important in early pathophysiology, stimulating cell migration and proliferation, as well as subsequent membrane contraction and vitreo-retinal traction, and Targeting hyalocytes early could mitigate advanced disease.

Hyalocytes in proliferative vitreo-retinal diseases

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Journal Info

Category	Quartile
OPHTHALMOLOGY	4