Summary. The aim of the study was to evaluate the effectiveness of domestic devices for supporting blood circulation in case of out-of-hospital circulatory arrest during preclinical trials. Research materials and methods. The study assessed the effectiveness of the Russian cardiac massager “CardioRobot” – an automated device for performing indirect cardiac massage of domestic design. This device has the following technical characteristics: piston type design; compression depth – (50-60±2) mm; compression frequency – (102±2) compressions/min; 2 operating modes – continuous and 30:2; weight – 6.5 kg; continuous battery life – 45 min; trapezoidal compression curve. To evaluate the device, a comparative experiment was conducted on large mammals (pigs), during which the work of the domestic prototype and the foreign device “LUCAS-2” was compared by comparing the indicators of central hemodynamics and gas exchange. During the clinical trials of LifeStream ECMO, postmortem extracorporeal membrane oxygenation (ECMO) of two donors was performed. During the experiment, the following were assessed: pO2, pH, pCO2, arterial blood lactate and creatinine concentrations. Research results and their analysis. During preclinical trials, domestically produced devices demonstrated experimental effectiveness comparable to similar foreign-made products. Currently, the LIFESTREAM ECMO perfusion emergency circulatory restoration complex for human resuscitation has received a certificate and is actively used in the Russian Federation, and the CardioRobot automated chest compression device is undergoing state registration.

V.M. Teplov

D.M. Prasol

E.A. Romanova

K.V. Filipenko

V.V. Kharlamov

A.A. Raevskiy

Disaster Medicine

Medicina Katastrof

Preclinical Testing of Domestic Devices Used in out-of-Hospital Circular Arrest

院外循环骤停国产设备临床前测试

Preclinical Testing of Domestic Devices Used in out-of-Hospital Circular Arrest

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