Objective: To explore biopsychosocial factors (beliefs, depression, catastrophizing cytokines) in individuals newly diagnosed with lung cancer and no pain to determine their relationship at diagnosis and across time and to determine whether these factors contribute to pain intensity or pain interference with function at pain onset. Materials and Methods: A longitudinal, exploratory, pilot study was implemented in a private medical center and a VA medical center in the southeast. Twelve subjects not experiencing pain related to cancer of the lung or its treatment were recruited. A Karnofsky status of 40% and hemoglobin of 8 g were required. Five questionnaires were completed and 10 mL of blood was drawn at baseline; 4 questionnaires and blood draws were repeated monthly for 5 months. One baseline questionnaire and a pain assessment were added at final. Demographic, clinical, and questionnaire data were summarized; standardized scale scores were calculated. Results: Biopsychosocial scores that were low at baseline increased from T1-T4 but decreased slightly T5-T6. Individuals with higher pain intensity and higher pain interference at final had higher psychosocial scores at baseline than individuals with lower pain intensity and lower pain interference at final. Conclusions: Unrelated to disease stage, metastasis, or treatment, unique levels of biopsychosocial factors are observed in patients newly diagnosed with lung cancer who report higher levels of pain intensity and higher levels of pain interference at the time pain occurs. Replication studies are needed to validate this response pattern and determine the value of repeated individual assessments.

Jo A. Dalton

Melinda K. Higgins

Andrew H. Miller

Francis J. Keefe

Fadlo R. Khuri

American Journal of Clinical Oncology

​​​​​​​American Journal of Clinical Oncology is a multidisciplinary journal for cancer surgeons, radiation oncologists, medical oncologists, GYN oncologists, and pediatric oncologists.

The emphasis of AJCO is on combined modality multidisciplinary loco-regional management of cancer. The journal also gives emphasis to translational research, outcome studies, and cost utility analyses, and includes opinion pieces and review articles.

The editorial board includes a large number of distinguished surgeons, radiation oncologists, medical oncologists, GYN oncologists, pediatric oncologists, and others who are internationally recognized for expertise in their fields.

The American Journal of Clinical Oncology: Cancer Clinical Trials is a multidisciplinary journal aimed at cancer surgeons, radiation oncologists, medical oncologists, GYN oncologists, and pediatric oncologists. The journal emphasizes combined modality multidisciplinary loco-regional management of cancer. It also focuses on translational research, outcome studies, and cost utility analyses, and includes opinion pieces and review articles. The editorial board consists of a large number of distinguished surgeons, radiation oncologists, medical oncologists, GYN oncologists, pediatric oncologists, and others who are internationally recognized for their expertise in their fields.

《American Journal of Clinical Oncology: Cancer Clinical Trials》是一本多学科期刊，面向癌症外科医生、放射肿瘤学家、内科肿瘤学家、妇科肿瘤学家和儿科肿瘤学家。期刊重点关注癌症的综合性多学科局部管理，同时也强调转化研究、结果研究和成本效用分析，并包含意见文章和综述文章。编辑委员会由众多在各自领域享有国际声誉的杰出外科医生、放射肿瘤学家、内科肿瘤学家、妇科肿瘤学家、儿科肿瘤学家等组成。

American Journal of Clinical Oncology: Cancer Clinical Trials

Pain Intensity and Pain Interference in Patients With Lung Cancer

Unrelated to disease stage, metastasis, or treatment, unique levels of biopsychosocial factors are observed in patients newly diagnosed with lung cancer who report higher levels of pain intensity and higher levelsof pain interference at the time pain occurs.

Category	Quartile
医学	4
医学, 肿瘤学	4

Pain Intensity and Pain Interference in Patients With Lung Cancer

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