Multisystem inflammatory syndrome in children (MIS-C) is a delayed postinflammatory disorder associated with the previous infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initially, MIS-C was described as highly similar to Kawasaki disease (KD), a pediatric febrile systemic vasculitis that can lead to the development of coronary artery aneurysms (CAAs). While KD and MIS-C are both inflammatory disorders, the 2 entities differ in their epidemiological, clinical, immunological, and pathological features. MIS-C clinical and laboratory characteristics are more closely related to toxic shock syndrome (TSS) than KD, which informs the understanding of pathogenesis and potential therapeutic approaches.

Magali Noval Rivas

Moshe Arditi

Rheumatic Disease Clinics of North America

风湿病诊所为您更新患者管理的最新趋势，让您了解最新进展，并为选择治疗方案提供良好的基础。每期（2 月、5 月、8 月和 11 月）都侧重于风湿病学的一个主题，并在经验丰富的编辑的指导下呈现。主题包括骨关节炎、类风湿性关节炎、晶体疾病、MSK 检查、骨骼疾病、免疫缺陷状态、狼疮、神经肌肉疾病、疼痛疾病、硬皮病、血管炎、儿科、疗法、治疗指南和治疗方式。

The Rheumatic Disease Clinics of North America aims to provide you with the latest trends and advancements in the management of rheumatic disease patients, helping you establish a solid foundation for treatment options. Each issue (February, May, August, and November) focuses on a specific theme in rheumatology, curated by an experienced editorial team. Topics include osteoarthritis, rheumatoid arthritis, crystal diseases, musculoskeletal examinations, bone diseases, immunodeficiency states, lupus, neuromuscular diseases, pain disorders, scleroderma, vasculitis, pediatrics, therapies, treatment guidelines, and treatment modalities.

《Rheumatic Disease Clinics of North America》致力于为您提供风湿病患者管理的最新趋势和进展，帮助您为治疗方案的选择打下坚实的基础。每期（2月、5月、8月和11月）聚焦于风湿病学的一个特定主题，内容由经验丰富的编辑团队精心编排。主题涵盖骨关节炎、类风湿性关节炎、晶体疾病、肌肉骨骼检查、骨骼疾病、免疫缺陷状态、狼疮、神经肌肉疾病、疼痛疾病、硬皮病、血管炎、儿科、疗法、治疗指南和治疗方式等。

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children

MIS-C clinical and laboratory characteristics are more closely related to toxic shock syndrome (TSS) than KD, which informs the understanding of pathogenesis and potential therapeutic approaches.

Category	Quartile
医学	4
医学, 风湿病学	4

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children

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