The fusion of synthetic biology and materials science offers exciting opportunities to produce sustainable materials that can perform programmed biological functions such as sensing and responding or enhance material properties through biological means. Bacterial cellulose (BC) is a unique material for this challenge due to its high-performance material properties and ease of production from culturable microbes. Research in the past decade has focused on expanding the benefits and applications of BC through many approaches. Here, we explore how the current landscape of BC-based biomaterials is being shaped by progress in synthetic biology. As well as discussing how it can aid production of more BC and BC with tailored material properties, we place special emphasis on the potential of using BC for engineered living materials (ELMs); materials of a biological nature designed to carry out specific tasks. We also explore the role of 3D bioprinting being used for BC-based ELMs and highlight specific opportunities that this can bring. As synthetic biology continues to advance, it will drive further innovation in BC-based materials and ELMs, enabling many new applications that can help address problems in the modern world, in both biomedicine and many other application fields.

Koray Malcı

Ivy S. Li

Natasha Kisseroudis

Tom Ellis

ACS Synthetic Biology

该杂志对新基因电路和基因产物的设计和合成研究特别感兴趣；系统设计中的计算方法；以及理解疾病和新陈代谢的综合应用方法。主题可能包括但不限于：遗传系统的设计和优化遗传电路设计及其组织成程序的原则帮助遗传系统设计的计算方法遗传部分量化的实验方法，电路和代谢通量基因部件库：它们的创建、分析和本体表示蛋白质工程，包括计算设计代谢工程和细胞制造，包括生物质转化自然产品获取、工程和生产细胞编程的创造性和创新应用医学应用、组织工程和编程治疗细胞最小细胞设计和构建基因组学和基因组替代策略病毒工程用于合成生物学的自动化和机器人组装平台DNA合成方法宏基因组学和合成宏基因组学分析生物信息学应用于基因发现、化学信息学和通路构建基因优化转录和代谢组学的基因组规模测量方法系统生物学和整合多个数据源的方法体外和无细胞合成生物学和分子编程核酸工程。

The journal ACS Synthetic Biology is particularly interested in the design and synthesis of new genetic circuits and gene products, computational methods in systems design, and integrative approaches to understanding diseases and metabolism. Topics may include, but are not limited to: design and optimization of genetic systems, principles of genetic circuit design and their organization, computational methods supporting genetic system design, quantitative experimental methods for genetic components, circuit and metabolic flux, creation, analysis, and ontological representation of gene component libraries, protein engineering (including computational design), metabolic engineering and cell manufacturing (including biomass conversion), acquisition, engineering, and production of natural products, creative and innovative applications of cell programming, medical applications, tissue engineering and programmed therapy, design and construction of minimal cells, genomics and genomic replacement strategies, viral engineering, automation and robotic assembly platforms for synthetic biology, DNA synthesis methods, metagenomics and synthetic metagenomics analysis, bioinformatics applications in gene discovery, cheminformatics and pathway construction, gene optimization, genome-scale measurement methods for transcriptomics and metabolomics, as well as systems biology and methods for integrating multiple data sources, in vitro and cell-free synthetic biology, molecular programming, and nucleic acid engineering.

《ACS Synthetic Biology》期刊特别关注新基因电路和基因产物的设计与合成研究，系统设计中的计算方法，以及理解疾病和新陈代谢的综合应用。主题包括但不限于：遗传系统的设计与优化、遗传电路设计及其组织原则、支持遗传系统设计的计算方法、遗传部分的量化实验方法、电路和代谢通量、基因部件库的创建、分析及本体表示、蛋白质工程（包括计算设计）、代谢工程和细胞制造（如生物质转化）、自然产品的获取、工程和生产、细胞编程的创新应用、医学应用、组织工程和编程治疗、最小细胞的设计与构建、基因组学和基因组替代策略、病毒工程、合成生物学的自动化和机器人组装平台、DNA合成方法、宏基因组学及合成宏基因组学分析、生物信息学在基因发现、化学信息学和通路构建中的应用、基因优化、转录和代谢组学的基因组规模测量方法，以及系统生物学和整合多个数据源的方法，体外和无细胞合成生物学及分子编程、核酸工程。

Category	Quartile
生物学	2
生物学, 生化研究方法	1

Modulating Microbial Materials - Engineering Bacterial Cellulose with Synthetic Biology

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Category	Quartile
BIOCHEMICAL RESEARCH METHODS	1