Abstract As the growth in resistance to bacterial infection treatments poses a grave threat to global health in the 21st century, there is a constant need to explore novel antibacterial agents that have the ability to overcome drug resistance. Indole‐containing alkaloids are widely distributed in nature, and a variety of indole‐containing alkaloids have already been applied in clinical practice, proving that indole‐containing alkaloids are fascinating and privileged scaffolds for the development of novel drugs. Moreover, indole‐containing alkaloids could exert their antibacterial activity through the inhibition of efflux pumps, the biofilm, filamentous temperature‐sensitive protein Z, and methicillin‐resistant Staphylococcus aureus pyruvate kinase; so, indole‐containing alkaloids constitute an important source of novel antibacterial agents. This review is an endeavor to highlight the advances in the development of indole‐containing alkaloids with antibacterial potential, covering articles published in the recent 10 years.

Yang Liu

Ying Cui

Liyan Lu

Yufeng Gong

Wen Han

Guishun Piao

Archiv der Pharmazie

ARCHIV DER PHARMAZIE - CHEMISTRY IN LIFE SCIENCES 是一份致力于药物和药物化学各个领域研究和开发的国际期刊。重点放在将合成有机化学、结构生物学、分子建模、生物有机化学、天然产物化学、生物化学或分析方法与生物活性等药物或医学方面相结合的论文。该期刊的重点是原创研究论文，但也欢迎其他具有科学价值的贡献（例如评论、小型评论、亮点、专题讨论会贡献、讨论和论文）。

ARCHIV DER PHARMAZIE - CHEMISTRY IN LIFE SCIENCES is an international journal dedicated to research and development in all areas of pharmaceuticals and pharmaceutical chemistry. The focus is on papers that integrate synthetic organic chemistry, structural biology, molecular modeling, bioorganic chemistry, natural product chemistry, biochemistry, or analytical methods with bioactivity related to drugs or medicine. The journal primarily publishes original research articles but also welcomes other scientifically valuable contributions, such as reviews, mini-reviews, highlights, contributions to special discussions, discussions, and papers.

《ARCHIV DER PHARMAZIE - CHEMISTRY IN LIFE SCIENCES》是一份国际期刊，专注于药物和药物化学的各个研究领域。期刊的重点在于将合成有机化学、结构生物学、分子建模、生物有机化学、天然产物化学、生物化学及分析方法与药物或医学相关的生物活性相结合。该期刊主要发表原创研究论文，同时也欢迎其他具有科学价值的贡献，如评论、小型评论、亮点、专题讨论会贡献、讨论和论文。

Arch Pharm

Natural indole‐containing alkaloids and their antibacterial activities

This review is an endeavor to highlight the advances in the development of indole‐containing alkaloids with antibacterial potential, covering articles published in the recent 10 years.

Category	Quartile
医学	3
医学, 化学综合	2
医学, 药学	2
医学, 药物化学	3

Natural indole‐containing alkaloids and their antibacterial activities

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Journal Info

Category	Quartile
PHARMACOLOGY & PHARMACY	1