It is well known that hyperthyroidism occurs in approximately 2 to 17.5% of patients with myasthenia gravis. Hyperthyroidism may influence the clinical course of myasthenia gravis. We report the cases of two patients, a 53-year-old man and an 18-year-old woman, who had both severe myasthenia gravis and hyperthyroidism due to Graves' disease. Myasthenia gravis affected in particular facio-ocular areas with diffuse myopathy and signs of neuromuscular block on the electromyogram. In one patient, the diagnosis of thyroid disease was made three months before the diagnosis of myasthenia gravis while in the other, thyroid disease was recognized four months after myasthenia gravis. Myasthenia gravis worsened after the development of hyperthyroidism in the second patient. Both patients were given anti-cholinesterase drugs. One underwent thymectomy. Radioiodine used for the treatment of hyperthyroidism improved the symptoms of myasthenia gravis in the first patient. The association of myasthenia gravis and hyperthyroidism is more than a coincidence; our cases illustrate the difficult diagnosis and management of these diseases. Clinicians should look for myasthenia gravis in hyperthyroid patients and vice versa, especially when symptoms of myasthenia gravis or hyperthyroidism worsen.

L Trabelsi

N Charfi

Ch Triki

M Mnif

N Rekik

Ch Mhiri

M Abid

Annales d'endocrinologie

法国内分泌学会 (SFE) 的喉舌ANNALES D'ENDOCRINOLOGIE 发表来自内分泌和代谢疾病的临床、治疗和基础研究的评论、文章和病例报告。每年，它都会发表一份工作立场文件——一组法语内分泌学家，研究由学会科学委员会选择的内分泌病理学。该杂志也是学会年会的机关，出版研讨会的总结、演讲和海报。《LES MUST DE L'ENDOCRINOLOGIE》是为大会推出的特别小册子，总结文章总是很深受好评。最后，我们发布了在 HENRI-PIERRE KLOTZ 国际内分泌日期间提供的高水平教学课程。 《年鉴》是世界的一扇窗户，让临床医生随时了解我们所有专业领域的诊断和治疗情况。

"Annales d'Endocrinologie" is the official journal of the French Society of Endocrinology (SFE), publishing reviews, articles, and case reports on clinical, therapeutic, and basic research in the field of endocrine and metabolic diseases. Each year, the journal releases a position paper prepared by a group of French-speaking endocrinologists, focusing on endocrine pathologies selected by the Society's Scientific Committee. Additionally, the journal serves as the official publication for the Society's annual meeting, summarizing workshops, presentations, and posters. The special booklet "LES MUST DE L'ENDOCRINOLOGIE" is launched during the conference and is well-received, summarizing key articles. Finally, we publish high-level educational courses provided during the HENRI-PIERRE KLOTZ International Endocrinology Day. "Annales d'Endocrinologie" serves as a window for clinicians to stay updated on the latest diagnostic and therapeutic developments across all areas of our specialty.

《Annales d'Endocrinologie》是法国内分泌学会（SFE）的官方期刊，发表内分泌和代谢疾病领域的临床、治疗和基础研究的评论、文章和病例报告。每年，该期刊都会发布一份工作立场文件，由一组法语内分泌学家研究由学会科学委员会选择的内分泌病理学。此外，该杂志也是学会年会的官方出版物，发布研讨会的总结、演讲和海报。特别小册子《LES MUST DE L'ENDOCRINOLOGIE》在大会期间推出，深受好评，汇总了相关的文章。最后，我们还发布了在HENRI-PIERRE KLOTZ国际内分泌日期间提供的高水平教学课程。《Annales d'Endocrinologie》为临床医生提供了一个了解各专业领域诊断和治疗最新进展的窗口。

Annales d'Endocrinologie

Ann Endocrinol (Paris)

[Myasthenia gravis and hyperthyroidism: two cases].

L’association myasthenie et hyperthyroidie est relativement frequente, le diagnostic respectif des deux pathologies est rendu difficile par la similarite des manifestations cliniques en particulier dans les formes oculaires.

Category	Quartile
医学	3
医学, 内分泌学与代谢	4

[Myasthenia gravis and hyperthyroidism: two cases].

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Journal Info

Category	Quartile
ENDOCRINOLOGY & METABOLISM	3