Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy over the past decade. Unfortunately, immune related adverse events (irAEs) are common, including rheumatologic adverse events. These rheumatologic irAEs include de novo rheumatoid arthritis-like presentations or flares of pre-existing rheumatoid arthritis, collectively called ICI-associated rheumatoid arthritis. In this article we review the different mechanisms of disease activity and management approaches including use of conventional (cs) DMARDs and biologic (b) DMARDs in this patient population. Other forms of ICI-induced inflammatory arthritis e.g., PMR-like or Spondylarthritis-type IA, are beyond the scope of this review.

Luigino Bernabela

Bonnie Bermas

Current Rheumatology Reports

该杂志旨在回顾风湿病学领域最近发表的最重要的研究。通过提供国际专家的清晰、有见地、平衡的贡献，该杂志旨在为所有参与风湿病护理和预防的人提供服务。我们通过任命国际权威担任关键学科领域的编辑来实现这一目标，例如许多关节炎、骨质疏松症和代谢性骨病，以及系统性红斑狼疮。反过来，部分编辑会选择主要专家发表综合评论文章的主题，这些文章强调新的发展和最近发表的重要论文，并通过带注释的参考列表突出显示。一个国际编辑委员会审查年度目录，建议其国家/地区特别感兴趣的文章，并确保主题是最新的并包括新兴研究。偶尔也会提供该领域知名人士的评论。

Current Rheumatology Reports aims to review the most significant recent research published in the field of rheumatology. The journal serves all those involved in the care and prevention of rheumatic diseases by providing clear, insightful, and balanced contributions from international experts. We achieve this by appointing leading authorities as editors in key subject areas, including various forms of arthritis, osteoporosis, metabolic bone disease, and systemic lupus erythematosus. Some editors select topics for comprehensive review articles written by leading experts, highlighting new developments and important recently published papers, accompanied by annotated reference lists. An international editorial board reviews the annual catalog, recommending articles of particular interest to their countries and ensuring that topics are current and include emerging research. Occasionally, commentaries from prominent figures in the field are also provided.

《Current Rheumatology Reports》旨在回顾风湿病学领域最近发表的重要研究。该杂志通过提供国际专家的清晰、有见地和公正的贡献，服务于所有参与风湿病护理和预防的人员。我们通过任命国际权威担任关键学科领域的编辑，涵盖多个主题，如关节炎、骨质疏松症、代谢性骨病以及系统性红斑狼疮。部分编辑会选择主要专家撰写综合评论文章，强调新发展和最近发表的重要论文，并附带注释的参考列表。国际编辑委员会审查年度目录，推荐各国特别感兴趣的文章，确保主题的前沿性和新兴研究的覆盖。此外，偶尔也会提供该领域知名人士的评论。

Category	Quartile
医学	2
医学, 风湿病学	2

Immune Checkpoint Inhibitor Associated Rheumatoid Arthritis

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