Traditional genetic counseling has focused on the target gene and its natural progress with respect to disease risk. Next-generation sequencing (NGS) can produce information on several genetic variants simultaneously, with different functions and consequences for each. Accordingly, determining the status of the patient or consultant and interpreting sequencing results from many genes can largely increase the complexity of genetic counseling. Moreover, the current environment of big data that can be readily shared via the internet and a ubiquitous network provides many different avenues for which a consultant must handle the traditional principle of genetic counseling in different ways. Thus, further consideration and rethinking of genetic counseling principles are necessary in the era of NGS. In this review, we discuss several aspects of genetic counseling that one can encounter when faced with NGS data.

Mina Yang

Jong-Won Kim

Annals of Laboratory Medicine

检验医学年鉴是韩国检验医学会的官方期刊。期刊名称最近从 2012 年 1 月号的韩国检验医学杂志 (ISSN, 1598-6535) 更改。ANN LAB MED 的 JCR 2017 影响因子为 1.916。

The Annals of Laboratory Medicine is the official journal of the Korean Society of Laboratory Medicine. The journal's name was changed from the Korean Journal of Laboratory Medicine (ISSN: 1598-6535) in the January 2012 issue. The JCR 2017 impact factor of the Annals of Laboratory Medicine is 1.916.

《Annals of Laboratory Medicine》是韩国检验医学会的官方期刊。该期刊的名称于2012年1月号时由《韩国检验医学杂志》（ISSN: 1598-6535）更改而来。《Annals of Laboratory Medicine》的JCR 2017影响因子为1.916。

Principles of Genetic Counseling in the Era of Next-Generation Sequencing

Several aspects of genetic counseling that one can encounter when faced with NGS data are discussed, including determining the status of the patient or consultant and interpreting sequencing results from many genes.

Category	Quartile
医学	2
医学, 医学实验技术	2

Principles of Genetic Counseling in the Era of Next-Generation Sequencing

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Journal Info

Category	Quartile
MEDICAL LABORATORY TECHNOLOGY	1