The biomechanical interaction of stents and the arteries into which they are deployed is a potentially important consideration for long-term success. Adverse arterial reactions to excessive stress and the resulting damage have been linked to the development of restenosis. Complex geometric features often encountered in these procedures can confound treatment. In some cases, it is desirable to deploy a stent across a region in which the diameter decreases significantly over the length of the stent. This study aimed to assess the final arterial diameter and circumferential stress in tapered arteries into which two different stents were deployed (one stiff and one less stiff). The artery wall was assumed to be made of a strain stiffening material subjected to large deformations, with a 10% decrease in diameter over the length of the stent. A commercially available finite element code was employed to solve the contact problem between the two elastic bodies. The stiffer stent dominated over arterial taper, resulting in a nearly constant final diameter along the length of the stent, and very high stresses, particularly at the distal end. The less stiff stent followed more closely the tapered contour of the artery, resulting in lower artery wall stresses. More compliant stents should be considered for tapered artery applications, perhaps even to the exclusion of tapered stents.

Lucas H Timmins

Clark A Meyer

Michael R Moreno

James E Moore

Annals of biomedical engineering

ANNALS OF BIOMEDICAL ENGINEERING是生物医学工程学会的官方期刊，发表生物工程和生物医学工程主要领域的原创文章。 《年鉴》是一本跨学科的国际期刊，旨在突出解决生物和生物医学问题的综合方法。

The Annals of Biomedical Engineering is the official journal of the Biomedical Engineering Society, dedicated to publishing original research articles in the fields of bioengineering and biomedical engineering. This interdisciplinary international journal aims to highlight integrated approaches to solving biological and biomedical problems.

《Annals of Biomedical Engineering》是生物医学工程学会的官方期刊，专注于发表生物工程和生物医学工程领域的原创研究文章。这本跨学科的国际期刊旨在强调解决生物和生物医学问题的综合方法。

Annals of Biomedical Engineering

Ann Biomed Eng

Mechanical modeling of stents deployed in tapered arteries.

The final arterial diameter and circumferential stress in tapered arteries into which two different stents were deployed (one stiff and one less stiff) was assessed, resulting in a nearly constant final diameter along the length of the stent, and very high stresses, particularly at the distal end.

Category	Quartile
医学	2
医学, 工程生物医学	3

Mechanical modeling of stents deployed in tapered arteries.

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